1202518-88-4

Basic information

• Product Name: 2-(2-fluoro-4-nitrophenyl)-1,4,5,6-tetrahydropyrimidine
• Synonyms: 2-(2-fluoro-4-nitrophenyl)-1,4,5,6-tetrahydropyrimidine
• CAS NO: 1202518-88-4
• Molecular Weight: 223.207
• Mol File: 1202518-88-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-fluoro-4-nitrophenyl)-1,4,5,6-tetrahydropyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-fluoro-4-nitrophenyl)-1,4,5,6-tetrahydropyrimidine(1202518-88-4)
• EPA Substance Registry System: 2-(2-fluoro-4-nitrophenyl)-1,4,5,6-tetrahydropyrimidine(1202518-88-4)

Safety Data

• Hazardous Substances Data: 1202518-88-4(Hazardous Substances Data)

Upstream product

• 109-76-2 Trimethylenediamine 
• 157701-72-9 4-nitro-2-fluorobenzaldehyde 

Relevant articles and documents

Efficient synthesis of pyrimido[1,2-c] [1,3]benzothiazin-6-imines and related tricyclic heterocycles by SNAr-type C-S, C-N, or C-O bond formation with heterocumulenes

(Chemical Equation Presented) A simple and practical synthetic method of pyrimido[1,2-c]-[1,3]benzothiazin-6-imines and related tricyclic heterocycles has been developed. Treatment of 2-(2-haloaryl)-tetrahydropyrimidines with NaH and a heterocumulene such as carbon disulfide, isothiocyanates, and isocyanates in DMF provides the desired cyclization products through a regioselective S NAr-type reaction. This method provides direct access to PD 404182 and related compounds.