120269-74-1

Basic information

• Product Name: (2R,3R,6S)-6-((2R,5R,6S)-5-Benzyloxy-5-ethyl-6-methyl-tetrahydro-pyran-2-yl)-2-(4-methoxy-benzyloxy)-heptane-1,3,6-triol
• Synonyms: (2R,3R,6S)-6-((2R,5R,6S)-5-Benzyloxy-5-ethyl-6-methyl-tetrahydro-pyran-2-yl)-2-(4-methoxy-benzyloxy)-heptane-1,3,6-triol
• CAS NO: 120269-74-1
• Molecular Weight: 516.675
• Mol File: 120269-74-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2R,3R,6S)-6-((2R,5R,6S)-5-Benzyloxy-5-ethyl-6-methyl-tetrahydro-pyran-2-yl)-2-(4-methoxy-benzyloxy)-heptane-1,3,6-triol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,6S)-6-((2R,5R,6S)-5-Benzyloxy-5-ethyl-6-methyl-tetrahydro-pyran-2-yl)-2-(4-methoxy-benzyloxy)-heptane-1,3,6-triol(120269-74-1)
• EPA Substance Registry System: (2R,3R,6S)-6-((2R,5R,6S)-5-Benzyloxy-5-ethyl-6-methyl-tetrahydro-pyran-2-yl)-2-(4-methoxy-benzyloxy)-heptane-1,3,6-triol(120269-74-1)

Safety Data

• Hazardous Substances Data: 120269-74-1(Hazardous Substances Data)

Upstream product

• 113981-32-1 (4R,5R)-1-<(2R,5R,6S)-5-benzyloxy-5-ethyl-6-methyltetrahydropyran-2-yl>-4,6-isopropylidenedioxy-5-(4-methoxybenzyloxy)hexan-1-one 
• 109536-52-9 [(3aR,6S,6aR)-6-(4-Methoxy-benzyloxy)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl]-methanol 
• 82529-87-1 (3aR,6S,6aR)-6-(4-Methoxy-benzyloxy)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole-5-carbaldehyde 
• 107207-30-7 (4R,5R)-4-Benzyloxymethyl-5-(4-methoxy-benzyloxy)-2,2-dimethyl-[1,3]dioxane 
• 69940-04-1 1-[(3aR,6S,6aR)-6-(4-Methoxy-benzyloxy)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl]-ethane-1,2-diol 
• 824-94-2 p-methoxybenzyl chloride 
• 329899-60-7 (3aR,6S,6aR)-5-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-6-(4-methoxy-benzyloxy)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole 
• 113643-37-1 (3aR,6S,6aR)-5-Benzyloxymethyl-6-(4-methoxy-benzyloxy)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole 
• 110672-03-2 <(2R,5R,6S)-5-benzyloxy-5-ethyl-6-methyltetrahydropyran-2-yl>-2-dimethoxyphosphonoethan-1-one 
• 113643-38-2 (2R,3R)-2,4-isopropylidenedioxy-3-(4-methoxybenzyloxy)butanal 
• 126394-13-6 methyl <(2R,5R,6S)-5-benzyloxy-5-ethyl-6-methyltetrahydropyran>-2-carboxylate 
• 126394-12-5 (2S,5S,6S)-5-Benzyloxy-5-ethyl-heptane-1,2,6-triol 
• 107207-31-8 (2R,3R)-2,4-isopropylidenedioxy-3-(4-methoxybenzyloxy)butanol 
• 113643-40-6 <(2R,5R,6S)-5-benzyloxy-5-ethyl-6-methyltetrahydropyran>-2-methanol 

Downstream Products

• 120269-75-2 (2R,3R,6S)-6-<(2R,5R,6S)-5-benzyloxy-5-ethyl-6-methyltetrahydropyran-2-yl>-3,6-bis(tert-butyldimethylsilyloxy)-2-(4-methoxybenzyloxy)heptan-1-ol 
• 108194-54-3 (R)-4-[(2S,9S,10S,12R,15R)-2-((2R,5R,6S)-5-Ethyl-5-hydroxy-6-methyl-tetrahydro-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxa-dispiro[4.1.5.3]pentadec-13-en-9-yl]-hexan-3-one 
• 113643-43-9 (3R,4S)-4-{(2S,3S,5R)-6-[(R)-3-[(S)-5-((2R,5R,6S)-5-Benzyloxy-5-ethyl-6-methyl-tetrahydro-pyran-2-yl)-2-methoxy-5-methyl-tetrahydro-furan-2-yl]-3-(4-methoxy-benzyloxy)-prop-1-ynyl]-6-methoxy-3,5-dimethyl-tetrahydro-pyran-2-yl}-hexan-3-ol 
• 126365-86-4 (1R,5R,7S)-1-[(S)-5-((2R,5R,6S)-5-Benzyloxy-5-ethyl-6-methyl-tetrahydro-pyran-2-yl)-2-methoxy-5-methyl-tetrahydro-furan-2-yl]-7-((4S,5S,6R)-5,6-diethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-1-(4-methoxy-benzyloxy)-5-methyl-oct-2-yn-4-ol 
• 113643-44-0 (R)-1-<(3R,5R,6S)-6-<(1R,2R)-2-acetoxy-1-ethylbutyl>-2-methoxy-3,5-dimethyltetrahydropyran-2-yl>-3-<(5S)-5-<(2R,5R,6S)-5-benzyloxy-5-ethyl-6-methyltetrahydropyran-2-yl>-2-methoxy-5-methyltetrahydrofuran-2-yl>-3-(4-methoxybenzyloxy)prop-1-yne 
• 113643-45-1 (1Z,3R)-1-<(3R,5R,6S)-6-<(1R,2R)-2-acetoxy-1-ethylbutyl>-2-methoxy-3,5-dimethyltetrahydropyran-2-yl>-3-<(5S)-5-<(2R,5R,6S)-5-benzyloxy-5-ethyl-6-methyltetrahydropyran-2-yl>-2-methoxy-5-methyltetrahydrofuran-2-yl>-3-(4-methoxybenzyloxy)prop-1-ene 
• 113656-58-9 (1R,5R,7S,8S,9S,10R)-1-<(2RS,5S)-5-<(2R,5R,6S)-5-benzyloxy-5-ethyl-6-methyltetrahydropyran-2-yl>-2-methoxy-5-methyltetrahydrofuran-2-yl>-9-ethyl-8,10-isopropylidenedioxy-1-(4-methoxybenzyloxy)-5,7-dimethyldodec-2-yn-4-one 
• 53003-10-4 salinomycin 
• 120269-81-0 C₅₇H₈₄O₁₂ 
• 120269-81-0 C₅₇H₈₄O₁₂ 
• 120269-89-8 (R)-4-[(2S,5S,7S,9S,10S,12R)-2-[(2R,5R,6S)-5-Ethyl-5-(4-methoxy-benzyloxy)-6-methyl-tetrahydro-pyran-2-yl]-15-(4-methoxy-benzyloxy)-2,10,12-trimethyl-1,6,8-trioxa-dispiro[4.1.5.3]pentadec-13-en-9-yl]-hexan-3-one 
• 120269-89-8 (R)-4-[(2S,5R,7S,9S,10S,12R)-2-[(2R,5R,6S)-5-Ethyl-5-(4-methoxy-benzyloxy)-6-methyl-tetrahydro-pyran-2-yl]-15-(4-methoxy-benzyloxy)-2,10,12-trimethyl-1,6,8-trioxa-dispiro[4.1.5.3]pentadec-13-en-9-yl]-hexan-3-one 
• 113643-46-2 (R)-4-[(2S,5S,7S,9S,10S,12R)-2-((2R,5R,6S)-5-Benzyloxy-5-ethyl-6-methyl-tetrahydro-pyran-2-yl)-15-(4-methoxy-benzyloxy)-2,10,12-trimethyl-1,6,8-trioxa-dispiro[4.1.5.3]pentadec-13-en-9-yl]-hexan-3-one 
• 113643-46-2 (R)-4-[(2S,5R,7S,9S,10S,12R)-2-((2R,5R,6S)-5-Benzyloxy-5-ethyl-6-methyl-tetrahydro-pyran-2-yl)-15-(4-methoxy-benzyloxy)-2,10,12-trimethyl-1,6,8-trioxa-dispiro[4.1.5.3]pentadec-13-en-9-yl]-hexan-3-one 

Relevant articles and documents

Highly stereocontrolled total synthesis of the polyether antibiotic salinomycin. II. Synthesis of right (C18-C30) segments from D-glucose, D-mannitol, and ethyl L-lactate

-

STEREOSELECTIVE SYNTHESIS OF THE MIDDLE (C10-C17) AND RIGHT (C18-C30) SEGMENTS, AND THEIR COUPLING TO COMPLETE A FORMAL SYNTHESIS OF THE POLYETHER ANTIBIOTIC SALINOMYCIN

The middle (C10-C17) and right (C18-C30) segments of the polyether antibiotic salinomycin were stereoselectively synthesized from D-glucose, D-mannitol, and ethyl L-lactate.Coupling of the two segments followed by construction of the bisketal ring system gave the C10-C30 segment, which was already converted to salinomycin by Kishy.