1203050-38-7

Basic information

• Product Name: 4-iodo-N-(quinolin-8-yl)benzamide
• Synonyms: 4-iodo-N-(quinolin-8-yl)benzamide
• CAS NO: 1203050-38-7
• Molecular Weight: 374.181
• Mol File: 1203050-38-7.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 4-iodo-N-(quinolin-8-yl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-iodo-N-(quinolin-8-yl)benzamide(1203050-38-7)
• EPA Substance Registry System: 4-iodo-N-(quinolin-8-yl)benzamide(1203050-38-7)

Safety Data

• Hazardous Substances Data: 1203050-38-7(Hazardous Substances Data)

Upstream product

• 312503-18-7 2-hydroxy-N-(quinolin-8-yl)benzamide 
• 33757-48-1 N-quinolin-8-yl-benzamide 
• 619-58-9 4-iodobenzoic acid 
• 578-66-5 8-amino quinoline 
• 1711-02-0 4-iodobenzoic acid chloride 

Downstream Products

• 1437789-57-5 C₂₆H₂₁N₃O₂ 
• 1437789-67-7 4-((4S)-5,5-dimethyl-2-oxo-4-phenyl-1,3-oxazolidin-3-yl)-N-8-quinolinylbenzamide 
• 1437789-58-6 C₂₆H₂₁N₃O₂ 
• 1437789-56-4 C₂₅H₂₀N₄O₂ 
• 1437789-59-7 C₂₆H₂₁N₃O₂ 
• 1437789-60-0 C₂₆H₂₁N₃O₂ 
• 1437789-62-2 C₂₁H₁₉N₃O₂ 
• 1437789-65-5 C₂₆H₂₀FN₃O₂ 
• 1437789-64-4 C₂₆H₂₀FN₃O₂ 
• 1437789-63-3 C₂₆H₂₀FN₃O₂ 

Relevant articles and documents

Synthesis of phthalic acid derivatives: Via Pd-catalyzed alkoxycarbonylation of aromatic C-H bonds with alkyl chloroformates

A Pd(ii)-catalyzed alkoxycarbonylation of aromatic C-H bonds with alkyl chloroformates has been developed. A broad range of benzamides and alkyl chloroformates are compatible with this protocol. The reaction is operationally simple and scalable. The direct group could be readily removed to access substituted phthalic acid esters (PAEs), 1,2-dibenzyl alcohols and phthalamides. Besides alkoxycarbonylation of benzamide β-C-H bonds, γ-alkoxycarbonylation of 2-phenylacetamide is also feasible.

C-H Amidation and Amination of Arenes and Heteroarenes with Amide and Amine using Cu-MnO as a Reusable Catalyst under Mild Conditions

An atom-economical and efficient route for the direct amidation and amination of aryl C-H bonds using our synthesized recyclable heterogeneous Cu-MnO catalyst is reported here. The direct C-H amidation was carried out using a simple amide without any prea

C-5 selective chlorination of 8-aminoquinoline amides using dichloromethane

An oxidant-free electrochemical regioselective chlorination of 8-aminoquinoline amides at ambient temperature in batch and continuous-flow was achieved. Inert DCM was used as the chlorinating reagent. Owing to the continuous-flow setup, the reaction scale

Catalyst- And oxidant-free electrochemical: para -selective hydroxylation of N -arylamides in batch and continuous-flow

Hydroxyl compounds serve as key building blocks in the preparation of biologically active natural products and drugs. Traditionally, hydroxylation of the aromatic ring is achieved using stoichiometric amounts of oxidants, which leads to low atom-economy, undesired by-products, potential explosion risk and environmental pollution. Recently, electrosynthesis has attracted increasing attention as it employs clean electrical energy to promote redox reactions avoiding the use of oxidants. However, due to the poor mass and heat transfers of batch cells, low productivity and selectivity limit its further application. Herein, we develop a catalyst-, oxidant-, acidic solvent- and quaternary ammonium salt-free electrochemical para-selective hydroxylation of N-arylamides at room temperature in batch and continuous-flow. This proposal features excellent position control and water, air and functional group tolerance. Also, it is easy to scale up with higher productivity and selectivity using a flow electrolysis cell.