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120355-42-2

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120355-42-2 Usage

Description

(3AS,4S,6R,6AR)-6-(6-chloro-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid is a complex organic molecule that features a chloro-substituted purine base and a furo[3,4-d][1,3]dioxole-4-carboxylic acid moiety. (3AS,4S,6R,6AR)-6-(6-chloro-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid is characterized by a tetrahydrofuran ring and a carboxylic acid functional group, which may contribute to its potential biological activity. Given the presence of common structural elements in biologically active molecules, further investigation into its chemical properties and possible applications is necessary.

Uses

Used in Pharmaceutical Development:
(3AS,4S,6R,6AR)-6-(6-chloro-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid is used as a potential pharmaceutical candidate for the development of new drugs. The presence of a chloro-substituted purine ring suggests that this compound may have modulatory effects on biological activity, which is often desirable in drug discovery. Its unique structure could be harnessed to target specific biological pathways or receptors, offering new therapeutic options.
Used in Chemical Research:
In the field of chemical research, (3AS,4S,6R,6AR)-6-(6-chloro-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid serves as a subject for studying the synthesis and modification of complex organic molecules. Understanding the reactivity and properties of this compound can provide insights into the design of new chemical entities with tailored properties for various applications.
Used in Biochemical Studies:
(3AS,4S,6R,6AR)-6-(6-chloro-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid is utilized in biochemical studies to explore its interactions with biological systems. (3AS,4S,6R,6AR)-6-(6-chloro-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid's structure, which includes elements commonly found in biologically active molecules, makes it a candidate for investigating its potential binding to proteins, enzymes, or other biomolecules, which could reveal new mechanisms of action or therapeutic targets.

Check Digit Verification of cas no

The CAS Registry Mumber 120355-42-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,3,5 and 5 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 120355-42:
(8*1)+(7*2)+(6*0)+(5*3)+(4*5)+(3*5)+(2*4)+(1*2)=82
82 % 10 = 2
So 120355-42-2 is a valid CAS Registry Number.

120355-42-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (3AS,4S,6R,6AR)-6-(6-chloro-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid

1.2 Other means of identification

Product number -
Other names 6-chloro-(2,3-O-isopropylidene-5-carboxy-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:120355-42-2 SDS

120355-42-2Relevant articles and documents

RUTHENIUM TETRAOXIDE: A MILD REAGENT FOR THE OXIDATION OF 2',3'-O-ISOPROPYLIDENE PURINE NUCLEOSIDES

Singh, Ambarish K.,Varma, Rajender S.

, p. 2307 - 2310 (1992)

2',3'-O-Isopropylidene purine nucleosides have been oxidized with ruthenium tetraoxide to provide the corresponding 5'-carboxylic acids in quantitative yields under neutral conditions.

SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5

-

Paragraph 00505-00506, (2020/10/20)

The disclosure is directed to methods of treating disease using compounds of Formula I, Formula II, Formula III, Formula IV, Formula V, or Formula VI:

SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 (PRMT5)

-

Paragraph 00511, (2018/09/12)

The disclosure is directed to compounds of Formula I, Formula II, Formula III, Formula IV, Formula V, or Formula VI: Methods of their use in inhibiting a protein arginine methyltransferase 5 (PRMT5) enzyme and treating disease, as well as methods of their preparation are also described.

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