1203607-73-1Relevant articles and documents
Differential stereocontrolled formation of tricyclic triterpenes by mutation of tyrosine 99 of the oxidosqualene-lanosterol cyclase from saccharomyces cerevisiae
Wu, Tung-Kung,Li, Wen-Hsuan,Chang, Cheng-Hsiang,Wen, Hao-Yu,Liu, Yuan-Ting,Chang, Yi-Chun
, p. 5731 - 5737 (2009)
The function of the Tyr99 residue from Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase (ERG7) was analyzed by constructing deletion, and site-saturated mutants. Two truncated intermediates, (13αH)- isomalabarica-14Z,17E,21-trien-3βol and. (13αH)
Alteration of the substrate's prefolded conformation and cyclization stereochemistry of oxidosqualene-lanosterol cyclase of saccharomyces cerevisiae by substitution at Phenylalanine 699
Wu, Tung-Kung,Chang, Cheng-Hsiang,Wen, Hao-Yu,Liu, Yuan-Ting,Li, Wen-Hsuan,Wang, Tsai-Ting,Shie, Wen-Shiang
scheme or table, p. 500 - 503 (2010/05/18)
[Chemical equaction presented] The Saccharomyces cerevisiae ERG7 Phe699 mutants produced one chair-chair-chair (C-C-C) and two chair-boat-chair (C-B-C) truncated tricyclic compounds, one tetracyclic 17α-exocyclic unrearranged intermediate, and