120375-57-7 Usage
Description
6-Phenylhexylamine, Hydrochloride (CAS# 120375-57-7) is an organic compound with the chemical formula C12H18ClN. It is a white to off-white solid and is primarily used in organic synthesis due to its unique chemical properties.
Uses
Used in Organic Synthesis:
6-Phenylhexylamine, Hydrochloride is used as a synthetic building block for the creation of various organic compounds. Its application in organic synthesis is due to its ability to undergo a range of chemical reactions, making it a versatile component in the development of new molecules with potential applications in various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 6-Phenylhexylamine, Hydrochloride is used as an intermediate in the synthesis of various drugs. Its unique chemical structure allows it to be a key component in the development of new medications, potentially contributing to the treatment of various diseases and conditions.
Used in Chemical Research:
6-Phenylhexylamine, Hydrochloride is also utilized in chemical research as a model compound to study various reaction mechanisms and to understand the behavior of similar organic compounds. This helps researchers in the development of new synthetic methods and the optimization of existing ones.
Used in Material Science:
In the field of material science, 6-Phenylhexylamine, Hydrochloride may be used in the development of novel materials with specific properties. Its unique chemical structure can contribute to the creation of materials with improved characteristics, such as enhanced stability, reactivity, or selectivity.
Overall, 6-Phenylhexylamine, Hydrochloride is a versatile compound with a wide range of applications across different industries, primarily due to its unique chemical properties and its role in organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 120375-57-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,3,7 and 5 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 120375-57:
(8*1)+(7*2)+(6*0)+(5*3)+(4*7)+(3*5)+(2*5)+(1*7)=97
97 % 10 = 7
So 120375-57-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H19N.ClH/c13-11-7-2-1-4-8-12-9-5-3-6-10-12;/h3,5-6,9-10H,1-2,4,7-8,11,13H2;1H
120375-57-7Relevant articles and documents
Benzoxazolone Carboxamides as Potent Acid Ceramidase Inhibitors: Synthesis and Structure-Activity Relationship (SAR) Studies
Bach, Anders,Pizzirani, Daniela,Realini, Natalia,Vozella, Valentina,Russo, Debora,Penna, Ilaria,Melzig, Laurin,Scarpelli, Rita,Piomelli, Daniele
supporting information, p. 9258 - 9272 (2015/12/23)
Ceramides are lipid-derived intracellular messengers involved in the control of senescence, inflammation, and apoptosis. The cysteine amidase, acid ceramidase (AC), hydrolyzes these substances into sphingosine and fatty acid and, by doing so, regulates their signaling activity. AC inhibitors may be useful in the treatment of pathological conditions, such as cancer, in which ceramide levels are abnormally reduced. Here, we present a systematic SAR investigation of the benzoxazolone carboxamides, a recently described class of AC inhibitors that display high potency and systemic activity in mice. We examined a diverse series of substitutions on both benzoxazolone ring and carboxamide side chain. Several modifications enhanced potency and stability, and one key compound with a balanced activity-stability profile (14) was found to inhibit AC activity in mouse lungs and cerebral cortex after systemic administration. The results expand our arsenal of AC inhibitors, thereby facilitating the use of these compounds as pharmacological tools and their potential development as drug leads.
SUBSTITUTED BENZOXAZOLONE DERIVATIVES AS ACID CERAMIDASE INHIBITORS, AND THEIR USE AS MEDICAMENTS
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Page/Page column 19; 39; 46, (2015/12/31)
The present invention relates to substituted benzoxazolone derivatives as acid ceramidase inhibitors, pharmaceutical compositions containing these inhibitors and methods of inhibiting acid ceramidase for the treatment of disorders in which modulation of the levels of ceramide is clinically relevant. The invention also provides substituted benzoxazolone derivatives for use in the treatment of cancer, inflammation, pain, inflammatory pain or pulmonary diseases.
