120450-07-9

Basic information

• Product Name: 2-AMINO-4-(4-CHLOROPHENYL)-1H-PYRROLE-3-CARBONITRILE
• Synonyms: 2-AMINO-4-(4-CHLOROPHENYL)-1H-PYRROLE-3-CARBONITRILE
• CAS NO: 120450-07-9
• Molecular Formula: C₁₁H₈ClN₃
• Molecular Weight: 217.65
• Mol File: 120450-07-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-AMINO-4-(4-CHLOROPHENYL)-1H-PYRROLE-3-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-4-(4-CHLOROPHENYL)-1H-PYRROLE-3-CARBONITRILE(120450-07-9)
• EPA Substance Registry System: 2-AMINO-4-(4-CHLOROPHENYL)-1H-PYRROLE-3-CARBONITRILE(120450-07-9)

Safety Data

• Hazardous Substances Data: 120450-07-9(Hazardous Substances Data)

Usage

Usage

Intermediate in the synthesis of pharmaceuticals and agrochemicals

Biological Activities

Anticancer properties
Antimicrobial properties
Anti-inflammatory properties

Research Interest

Diverse applications make it of interest to researchers and chemists in various fields.

Upstream product

• 6660-08-8 N-(2-(4-chlorophenyl)-2-oxoethyl)acetamide 
• 109-77-3 malononitrile 
• 5467-71-0 4-chlorophenacylamine hydrochloride 
• 937-20-2 p-chlorophenacyl chloride 
• 7644-03-3 2-amino-1-(4-chlorophenyl)ethanone 

Downstream Products

• 120450-17-1 7-(4-Chloro-phenyl)-2-methyl-4-oxo-1,4-dihydro-pyrrolo[1,2-a]pyrimidine-8-carbonitrile 
• 120450-13-7 7-(4-Chloro-phenyl)-2,4-dimethyl-pyrrolo[1,2-a]pyrimidine-8-carbonitrile 
• 120450-14-8 7-(4-Chloro-phenyl)-2-methyl-4-phenyl-pyrrolo[1,2-a]pyrimidine-8-carbonitrile 
• 127720-26-7 7-(4-Chloro-phenyl)-8-cyano-4-oxo-1,4-dihydro-pyrrolo[1,2-a]pyrimidine-3-carboxylic acid ethyl ester 
• 127720-43-8 2-{[4-(4-Chloro-phenyl)-3-cyano-1H-pyrrol-2-ylamino]-methylene}-malonic acid diethyl ester 
• 127720-39-2 7-(4-Chloro-phenyl)-8-cyano-1-ethyl-4-oxo-1,4-dihydro-pyrrolo[1,2-a]pyrimidine-3-carboxylic acid 
• 127720-33-6 7-(4-Chloro-phenyl)-8-cyano-1-ethyl-4-oxo-1,4-dihydro-pyrrolo[1,2-a]pyrimidine-3-carboxylic acid ethyl ester 
• 120450-23-9 7-(4-Chloro-phenyl)-2,4-dimethyl-pyrrolo[1,2-a]pyrimidine-8-carboxylic acid amide 
• 120450-26-2 7-(4-Chloro-phenyl)-2-methyl-4-oxo-1,4-dihydro-pyrrolo[1,2-a]pyrimidine-8-carboxylic acid amide 
• 120450-24-0 7-(4-Chloro-phenyl)-2-methyl-4-phenyl-pyrrolo[1,2-a]pyrimidine-8-carboxylic acid amide 
• 1151652-95-7 5-(4-chlorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 

Relevant articles and documents

MODULATION OF PROTEIN TRAFFICKING

Compounds and compositions are provided for treatment or amelioration of one or more disorders characterized by defects in protein trafficking. A method of treating a disorder characterized by impaired protein trafficking includes administering to a subject or contacting a cell with a compound of Formula I: [formula here] or pharmaceutically acceptable salts or derivatives thereof.

Synthesis of 4-oxopyrrolopyrimidine-3-carboxylic acid derivatives as potential antimicrobial agents

A route for the synthesis of various derivatives of 4-oxopyrrolopyrimidine-3-carboxylic acid from 2-amino-3-cyano-4,5-dimethylpyrrole and 2-amino-3-cyano-4-arylpyrroles is described.