1204535-11-4

Basic information

• Product Name: (3S)-3-methyl-1-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine
• Synonyms: (3S)-3-methyl-1-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine
• CAS NO: 1204535-11-4
• Molecular Weight: 308.325
• Mol File: 1204535-11-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (3S)-3-methyl-1-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: (3S)-3-methyl-1-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine(1204535-11-4)
• EPA Substance Registry System: (3S)-3-methyl-1-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine(1204535-11-4)

Safety Data

• Hazardous Substances Data: 1204535-11-4(Hazardous Substances Data)

Usage

Description

(3S)-3-methyl-1-[4-(trifluoromethyl)phenyl]sulfonylpiperazine is a piperazine derivative with a molecular formula of C13H16F3N3O2S and a molecular weight of 349.34 g/mol. It features a sulfonamide group and a trifluoromethylphenyl moiety, which may interact with biological targets in the body. This chemical compound is commonly used in pharmaceutical research and development due to its potential therapeutic applications.

Uses

Used in Pharmaceutical Research and Development:
(3S)-3-methyl-1-[4-(trifluoromethyl)phenyl]sulfonylpiperazine is used as a potential drug candidate for the treatment of various diseases and disorders. Its specific pharmacological and toxicological properties are still under investigation, but it shows promise in this application due to its unique chemical structure and potential interactions with biological targets.

Upstream product

• 1204926-01-1 C₁₇H₂₃F₃N₂O₄S 
• 2991-42-6 4-trifluorophenylsulfonyl chloride 
• 74879-18-8 (S)-2-methylpiperazine 

Downstream Products

• 1204925-53-0 3-[((2S)-2-Methyl-4-{[4-(trifluoromethyl)phenyl]sulfonyl}-1-piperazinyl)carbonyl]pyrazolo[1,5-a]pyrimidine 
• 1204925-71-2 6-bromo-3-[((2S)-2-methyl-4-{[4-(trifluoromethyl)phenyl]sulfonyl}-1-piperazinyl)carbonyl]pyrazolo[1,5-a]pyrimidine 
• 1204925-66-5 6-Fluoro-3-[((2S)-2-methyl-4-{[4-(trifluoromethyl)phenyl]sulfonyl}-1-piperazinyl)carbonyl]pyrazolo[1,5-a]pyrimidine 
• 1204535-74-9 (2S)-1-[(6-fluoro-4-methyl-3-pyridinyl)carbonyl]-2-methyl-4-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine 
• 1204535-71-6 (2S)-1-[(6-chloro-2-methyl-3-pyridinyl)carbonyl]-2-methyl-4-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine 
• 1204535-76-1 (2S)-1-[(2,6-Dimethyl-3-pyridinyl)carbonyl]-2-methyl-4-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine 
• 1204535-42-1 (2S)-2-Methyl-1-[(6-methyl-3-pyridinyl)carbonyl]-4-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine 
• 1204535-75-0 (2S)-1-[(5-Bromo-3-pyridinyl)carbonyl]-2-methyl-4-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine 
• 1204535-58-9 5-[((2S)-2-Methyl-4-{[4-(trifluoromethyl)phenyl]sulfonyl}-1-piperazinyl)carbonyl]-2-pyridinecarbonitrile 
• 1204535-64-7 (2S)-2-Methyl-1-[(4-methyl-3-pyridinyl)carbonyl]-4-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine 
• 1204535-44-3 (2S)-2-methyl-1-[(2-methyl-3-pyridinyl)carbonyl]-4-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine 
• 1204535-60-3 (2S)-2-Methyl-1-{[2-(methyloxy)-3-pyridinyl]carbonyl}-4-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine 
• 1204535-61-4 (2S)-2-Methyl-1-[(5-methyl-3-pyridinyl)carbonyl]-4-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine 
• 1204535-59-0 (2S)-2-Methyl-1-{[6-(methyloxy)-3-pyridinyl]carbonyl}-4-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine 

Relevant articles and documents

PIPERAZINE DERIVATIVES FOR BLOCKING Cav2.2 CALCIUM CHANNELS

The present invention relates to novel piperazine compounds; to pharmaceutical compositions containing the compounds; and to the use of the compounds in therapy to treat diseases for which blocking the Cav2.2 calcium channels is beneficial and to treat diseases for which blocking the Cav2.2 and Cav3.2 calcium channels is beneficial, e.g. to treat pain.

Novel Derivatives

The present invention relates to novel piperazine derivatives; to processes for their preparation; to pharmaceutical compositions containing the derivatives; and to the use of the derivatives in therapy to treat diseases for which blocking the Cav2.2 calcium channels is beneficial.