1204768-66-0

Basic information

• Product Name: (E)-N'-((4-methylphenyl)sulfonyl)-N,N-dipropylformimidamide
• Synonyms: (E)-N'-((4-methylphenyl)sulfonyl)-N,N-dipropylformimidamide
• CAS NO: 1204768-66-0
• Molecular Weight: 282.407
• Mol File: 1204768-66-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (E)-N'-((4-methylphenyl)sulfonyl)-N,N-dipropylformimidamide(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-N'-((4-methylphenyl)sulfonyl)-N,N-dipropylformimidamide(1204768-66-0)
• EPA Substance Registry System: (E)-N'-((4-methylphenyl)sulfonyl)-N,N-dipropylformimidamide(1204768-66-0)

Safety Data

• Hazardous Substances Data: 1204768-66-0(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 941-55-9 4-toluenesulfonyl azide 
• 142-84-7 di-n-propylamine 
• 102-69-2 tri-n-propylamine 

Relevant articles and documents

Transition metal- And catalyst-free one-pot green method for the synthesis of: N -sulfonyl amidines via direct reaction of sulfonyl azides with amines

In this report, a green synthesis of N-sulfonyl amidines via the direct reaction of tertiary or secondary amines with sulfonyl azides is described. Transition metal- and catalyst-free conditions were used for the synthesis of biologically important N-sulfonyl amidines. Further studies showed that the reaction proceeded via in situ aerobic oxidation of amines under reflux conditions.

Photoinduced Cascade Reaction of Tertiary Amines with Sulfonyl Azides: Synthesis of Amidine Derivatives

A metal-free cascade reaction of tertiary amines with sulfonyl azides promoted by acridinium salts under blue light irradiation was developed and provided amidine derivatives in moderate to good yields. Enamine was generated from tertiary amine via single-electron transfer promoted by acridinium salts, and the following [3+2] cyclization with sulfonyl azide and CH2N2 release afforded the desired products. (Figure presented.).

Synthesis of N-Sulfonylformamidines by tert-butyl Hydroperoxide–Promoted, metal-free, direct oxidative dehydrogenation of aliphatic amines

A direct and convenient metal-free method to prepare sulfonyl amidines in the presence of aqueous tert-butyl hydroperoxide (T-HYDRO) has been developed. Different tertiary and secondary amines were tested for compatibility with the oxidative conditions and could be coupled with sulfonyl azides to form the corresponding amidines in moderate to good yields.