120483-06-9

Basic information

• Product Name: Propanal, 3-[(4-methylphenyl)thio]-
• CAS NO: 120483-06-9
• Molecular Formula: C10H12OS
• Molecular Weight: 180.271
• Mol File: 120483-06-9.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Propanal, 3-[(4-methylphenyl)thio]-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanal, 3-[(4-methylphenyl)thio]-(120483-06-9)
• EPA Substance Registry System: Propanal, 3-[(4-methylphenyl)thio]-(120483-06-9)

Safety Data

• Hazardous Substances Data: 120483-06-9(Hazardous Substances Data)

Upstream product

• 201230-82-2 carbon monoxide 
• 16336-54-2 p-tolyl vinyl sulfide 
• 106-45-6 para-thiocresol 
• 107-02-8 acrolein 

Downstream Products

• 1415575-81-3 C₂₆H₃₂O₂S 
• 1415577-54-6 C₁₅H₁₈O₂S 
• 1415577-53-5 C₁₇H₁₉O₄S^(1-)*Na⁽¹⁺⁾ 
• 1415577-52-4 C₁₃H₁₆OS 
• 3147-28-2 3-[(4-methylphenyl)sulfanyl]-1-propanol 
• 1269416-92-3 2-[2-(4-methylphenyl)thioethyl]-1,3-dioxolane 
• 16491-20-6 (R)-1-methyl-4-(phenylsulfinyl)benzene 
• 640-57-3 phenyltolylsulfone 
• 1269416-94-5 2-[(SS,2S)-2-chloro-2-(4-methylphenyl)sulfinylethyl]-1,3-dioxolane 

Relevant articles and documents

HERBICIDE COMPOSITION

There is provided a herbicidal composition containing a cyclohexanone compound represented by Formula (I) and at least one compound selected from Group A. Group A: consisting of benoxacor, cloquintocet-mexyl, cyometrinil, dichlormid, fenchlorazole-ethyl,

Investigation of functionalized α-chloroalkyllithiums for a stereospecific reagent-controlled homologation approach to the analgesic alkaloid (-)-epibatidine

Four putative functionalized α-chloroakyllithiums RCH 2CHLiCl, where R=CHCH2 (18 a), CCH (18 b), CH 2OBn (18 c), and CH[O(CH2)2O] (18 d), were generated in situ by sulfoxide-lithium exchange from α-chlorosulfoxides, and investigated for the stereospecific reagent-controlled homologation (StReCH) of phenethyl and 2-chloropyrid-5-yl (17) pinacol boronic esters. Deuterium labeling experiments revealed that α-chloroalkyllithiums are quenched by proton transfer from their α-chlorosulfoxide precursors and it was established that this effect compromises the yield of StReCH reactions. Use of α-deuterated α-chlorosulfoxides was discovered to ameliorate the problem by retarding the rate of acid-base chemistry between the carbenoid and its precursor. Carbenoids 18 a and 18 b showed poor StReCH efficacy, particularly the propargyl group bearing carbenoid 18 b, the instability of which was attributed to a facile 1,2-hydride shift. By contrast, 18 d, a carbenoid that benefits from a stabilizing interaction between O and Li atoms gave good StReCH yields. Boronate 17 was chain extended by carbenoids 18 a, 18 b, and 18 d in 16, 0, and 68 % yield, respectively; α-deuterated isotopomers D-18 a and D-18 d gave yields of 33 and 79 % for the same reaction. Double StReCH of 17 was pursued to target contiguous stereodiads appropriate for the total synthesis of (-)-epibatidine (15). One-pot double StReCH of boronate 17 by two exposures to (S)-D-18 a (≤66 % ee), followed by work-up with KOOH, gave the expected stereodiad product in 16 % yield (d.r.～67:33). The comparable reaction using two exposures to (S)-D-18 d (≤90 % ee) delivered the expected bisacetal containing stereodiad (R,R)-DD-48 in 40 % yield (≥98 % ee, d.r.=85:15). Double StReCH of 17 using (S)-D-18 d (≤90 % ee) followed by (R)-D-18 d (≤90 % ee) likewise gave (R,S)-DD-48 in 49 % yield (≥97 % ee, d.r.=79:21). (R,S)-DD-48 was converted to a dideuterated isotopomer of a synthetic intermediate in Corey's synthesis of 15. Copyright

Total synthesis of (±)-phytochromobilin starting from two pyrrole derivatives

(±)-Phytochromobilin was synthesized as an acid form by developing a convenient method for the preparation of A- and D-rings starting from a 2- tosylpyrrole derivative, followed by efficient construction of A/B- and C/D- ring components via Wittig-type coupling reaction of 5-tosylpyrrolinones with 2-formylpyrrole, and palladium catalyzed deprotection of allyl esters of propanoic acid side chains at C-8 and C-12.