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120500-15-4

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  • Spiro[1,2-dithiolane-3,6'-[19]thia[3,20]diazabicyclo[15.2.1]eicosa[1(20),9,13,15,17]pentaene]-4',5,12'-trione,4,11'-dihydroxy-2',4,9'-trimethyl-, 2-oxide, (2S,2'R,3R,4R,9'E,11'R,13'E,15'Z)-

    Cas No: 120500-15-4

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120500-15-4 Usage

General Description

Leinamycin is a complex natural product derived from the actinomycete Micromonospora griseorubida, which possesses potent antitumor activity. leinamycin contains a unique chlorinated benzoxazole core structure, which is responsible for its mechanism of action as a DNA-cleaving agent. Leinamycin displays selective cytotoxicity towards cancer cells by targeting the minor groove of DNA and inducing double-strand breaks, leading to DNA damage and cell death. Additionally, leinamycin has been shown to exhibit efficacy against drug-resistant cancer cells and is considered a promising candidate for the development of novel anticancer drugs.

Check Digit Verification of cas no

The CAS Registry Mumber 120500-15-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,5,0 and 0 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 120500-15:
(8*1)+(7*2)+(6*0)+(5*5)+(4*0)+(3*0)+(2*1)+(1*5)=54
54 % 10 = 4
So 120500-15-4 is a valid CAS Registry Number.
InChI:InChI=1/C22H26N2O6S3/c1-13-8-9-22(21(3,29)20(28)32-33(22)30)11-18(27)23-14(2)19-24-15(12-31-19)6-4-5-7-16(25)17(26)10-13/h4-7,10,12,14,17,26,29H,8-9,11H2,1-3H3,(H,23,27)/b6-4-,7-5-,13-10-

120500-15-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name LEINAMYCIN

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:120500-15-4 SDS

120500-15-4Downstream Products

120500-15-4Relevant articles and documents

Total synthesis of (+)-leinamycin

Kanda,Fukuyama

, p. 8451 - 8452 (2007/10/02)

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