1205537-80-9 Usage
Description
(R)-3,3'-bis(4-tert-butylphenyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl-2,2'-diol is a chemical compound known for its chiral properties, which are highly valued in the fields of chemistry and pharmaceuticals. As a derivative of 1,1'-binaphthyl, a well-established chiral scaffold, this compound plays a crucial role in asymmetric synthesis, where it can selectively control the stereochemistry of specific chemical reactions. Its unique structure and properties make it an indispensable tool for controlling chirality in organic synthesis, particularly in the production of pharmaceuticals and other fine chemicals. Furthermore, it has been investigated for its potential applications in chiral separation and molecular recognition.
Uses
Used in Chemical Synthesis:
(R)-3,3'-bis(4-tert-butylphenyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl-2,2'-diol is used as a chiral ligand in asymmetric catalysis for controlling the stereochemistry of certain chemical reactions. Its ability to selectively influence the outcome of these reactions makes it a valuable asset in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (R)-3,3'-bis(4-tert-butylphenyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl-2,2'-diol is used as a key component in the development and production of various drugs. Its chiral properties allow for the creation of enantiomerically pure compounds, which are essential for the efficacy and safety of many medications.
Used in Chiral Separation:
(R)-3,3'-bis(4-tert-butylphenyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl-2,2'-diol is employed in chiral separation techniques, where it aids in the isolation and identification of individual enantiomers of chiral compounds. This is particularly important in the pharmaceutical and chemical industries, as the different enantiomers of a compound can have vastly different properties and effects.
Used in Molecular Recognition:
(R)-3,3'-bis(4-tert-butylphenyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl-2,2'-diol is also utilized in the field of molecular recognition, where its chiral nature allows for the selective binding and interaction with specific target molecules. This can be applied in various research and diagnostic applications, as well as in the development of new materials and technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 1205537-80-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,5,5,3 and 7 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1205537-80:
(9*1)+(8*2)+(7*0)+(6*5)+(5*5)+(4*3)+(3*7)+(2*8)+(1*0)=129
129 % 10 = 9
So 1205537-80-9 is a valid CAS Registry Number.
1205537-80-9Relevant articles and documents
Synthesis and structural aspects of N-triflylphosphoramides and their calcium salts'highly acidic and effective Bronsted acids
Rueping, Magnus,Nachtsheim, Boris J.,Koenigs, Rene M.,Ieawsuwan, Winai
experimental part, p. 13116 - 13126 (2011/02/24)
Recently, 1,1′-bi-2-naphthol (BINOL)-based N-triflylphosphoramides emerged as a new class of potent Bronsted acid catalysts. In this paper we describe the efficient synthesis of various BINOL-based N- triflylphosphoramides and their calcium salts. Furthermore, X-ray crystal structure analysis combined with energy-dispersive X-ray spectroscopy (EDX) measurements confirmed that the synthesised chiral N-triflylphosphoramides are highly acidic metal-free catalysts. Freedom! The synthesis and structure determination of various 1,1′-bi-2-naphthol (BINOL)-based N-triflylphosphoramides and their corresponding calcium salts is presented. A simple acidic treatment of the calcium salts provides the metal-free Bronsted acids (see scheme; Tf=trifluoromethanesulfonyl).
