120570-09-4 Usage
Description
(S-(R S))-(+)-N-(1-PHENYLETHYL)-1-AZ&, also known as (3R)-N-[(1S)-1-Phenylethyl]-1-azabicyclo[2.2.2]octan-3-amine Dihydrochloride, is a derivative of 3-Quinuclidinone Hydrochloride (Q795795). It is a chemical compound with a specific stereochemistry and structure, which plays a crucial role in its applications and interactions.
Uses
Used in Pharmaceutical Synthesis:
(S-(R S))-(+)-N-(1-PHENYLETHYL)-1-AZ& is used as an intermediate in the synthesis of cevimeline, a thiolating agent. This application is due to its unique chemical structure, which allows for the formation of cevimeline through a series of chemical reactions.
Used in the Preparation of Cannabinoid Receptor Ligands:
In the field of medicinal chemistry, (S-(R S))-(+)-N-(1-PHENYLETHYL)-1-AZ& is used as a starting material for the preparation of novel CB1 and CB2 cannabinoid receptor ligands. The compound's specific stereochemistry and structure make it suitable for the development of these ligands, which can potentially be used in the treatment of various medical conditions related to the endocannabinoid system.
Used in the Chemical Industry:
(S-(R S))-(+)-N-(1-PHENYLETHYL)-1-AZ& may also find applications in the chemical industry, where it can be used as a building block for the synthesis of other complex organic molecules. Its unique structure and reactivity make it a valuable component in the development of new compounds with potential applications in various fields, such as materials science, pharmaceuticals, and agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 120570-09-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,5,7 and 0 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 120570-09:
(8*1)+(7*2)+(6*0)+(5*5)+(4*7)+(3*0)+(2*0)+(1*9)=84
84 % 10 = 4
So 120570-09-4 is a valid CAS Registry Number.
InChI:InChI=1/C15H22N2.2ClH/c1-12(13-5-3-2-4-6-13)16-15-11-17-9-7-14(15)8-10-17;;/h2-6,12,14-16H,7-11H2,1H3;2*1H/t12-,15-;;/m0../s1
120570-09-4Relevant articles and documents
Improved preparation of (R) and (S)-3-aminoquinuclidine dihydrochloride
Kowalczyk, Bruce A.,Rohloff, John C.,Dvorak, Charles A.,Gardner, John O.
, p. 2009 - 2015 (2007/10/03)
An improved procedure for the synthesis of either (R) or (S)-3-aminoquinuclidine was developed. Key intermediate imine 2 was made in a one pot process using lithium oxide as the base and molecular sieves.
Enantiomers of absolute configuration S of amide derivatives of 3-aminoquinuclidine, the process for preparing them and their application in therapy
-
, (2008/06/13)
Enantiomer of absolute configuration S of formula: STR1 where: X=O or S; and Ar denotes a: * phenyl ring substituted with one, two or three C1 -C4 alkoxy groups; * phenyl ring substituted at the 2-position with a OCH3 group and at the 5-position with a halogen atom or a lower alkylcarbonyl group; * phenyl ring substituted at the 2-position with OCH3, at the 4-position with NH2 or alkylcarbonyl-NH and at the 5-position with a halogen; * 3-fluoro-2-methoxyphenyl group; * 5-pyrimidinyl group substituted at the 2-position with NH2 and in the 4-position with alkoxy or phenyloxy. These compounds are useful as medicinal products having activity in respect of gastric movements and antiemetic activity.
