1206209-06-4

Basic information

• Product Name: S₄-(2-hydroxyethyl)-4-methylmorpholin-4-ium 4-methylbenzenesulfonate
• Synonyms: S₄-(2-hydroxyethyl)-4-methylmorpholin-4-ium 4-methylbenzenesulfonate
• CAS NO: 1206209-06-4
• Molecular Weight: 317.406
• Mol File: 1206209-06-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: S₄-(2-hydroxyethyl)-4-methylmorpholin-4-ium 4-methylbenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: S₄-(2-hydroxyethyl)-4-methylmorpholin-4-ium 4-methylbenzenesulfonate(1206209-06-4)
• EPA Substance Registry System: S₄-(2-hydroxyethyl)-4-methylmorpholin-4-ium 4-methylbenzenesulfonate(1206209-06-4)

Safety Data

• Hazardous Substances Data: 1206209-06-4(Hazardous Substances Data)

Upstream product

• 622-40-2 2-(morpholin-4-yl)ethanol 
• 80-48-8 methyl p-toluene sulfonate 

Relevant articles and documents

Dialkylamino and nitrogen heterocyclic analogues of hexadecylphosphocholine and cetyltrimetylammonium bromide: Effect of phosphate group and environment of the ammonium cation on their biological activity

A series of dialkylamino and nitrogen heterocyclic analogues of hexadecylphosphocholine and cetyltrimethylammonium bromide have been synthesized. The prepared compounds exhibit significant cytotoxic, antifungal and antiprotozoal activities. Alkylphosphocholines possess higher antifungal activity against Candida albicans in comparison with quaternary ammonium compounds. However, quaternary ammonium compounds exhibit significant higher activity against human tumor cells and Acanthamoeba lugdunensis compared to alkylphosphocholines. In addition, their haemolytic toxicity has been investigated. The relationship between structure and biological activity of the tested compounds is discussed.

COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS

This disclosure provides improved lipid-based compositions, including lipid nanoparticle compositions, and methods of use thereof for delivering agents in vivo including nucleic acids and proteins. These compositions are not subject to accelerated blood clearance and they have an improved toxicity profile in vivo.