120627-43-2

Basic information

• Product Name: 1H-Indole, 2-methyl-5-nitro-1-(phenylmethyl)-
• CAS NO: 120627-43-2
• Molecular Formula: C16H14N2O2
• Molecular Weight: 266.299
• Mol File: 120627-43-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1H-Indole, 2-methyl-5-nitro-1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 2-methyl-5-nitro-1-(phenylmethyl)-(120627-43-2)
• EPA Substance Registry System: 1H-Indole, 2-methyl-5-nitro-1-(phenylmethyl)-(120627-43-2)

Safety Data

• Hazardous Substances Data: 120627-43-2(Hazardous Substances Data)

Upstream product

• 95-20-5 2-methyl-1H-indole 
• 7570-47-0 5-nitro-2-methylindole 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 

Downstream Products

• 1025821-83-3 (1-Benzyl-2-methyl-5-nitro-1H-indol-3-yl)-oxo-acetyl chloride 
• 164083-71-0 2-methyl-5-nitro-1-(phenylmethyl)-1H-indole-3-glyoxylic acid amide 
• 164084-36-0 2-methyl-5-nitro-1-(phenylmethyl)-1H-indole-3-acetamide 
• 164083-72-1 2-methyl-5-nitro-1-(phenylmethyl)-1H-indole-3-glycolic acid amide 
• 120627-53-4 1-Benzyl-2-methyl-5-nitro-4-(toluene-4-sulfonylmethyl)-1H-indole 
• 133415-09-5 2,5-Dibenzyl-8-nitro-5H-pyrido[4,3-b]indol-2-ium; chloride 
• 133415-01-7 1-benzyl-2-(β-dimethylamino)vinyl-3-formyl-5-nitroindole 
• 133415-05-1 6-nitro-9-benzyl-γ-carboline 
• 111055-28-8 1-Benzyl-2-methyl-5-nitro-1H-indole-3-carboxaldehyde 

Relevant articles and documents

ACETALS OF LACTAMS AND ACID AMIDES. 60. NOVEL APPROACH TO THE SYNTHESIS OF γ-CARBOLINES

N-Alkylation of 2-methyl-5-nitroindole followed by the Vilsmeyer reaction has given some 2-methyl-3-formyl-5-nitro-N-alkylindoles, which on reaction with DMF diethyl acetal afford 2-(β-dimethylamino)vinylindoles.Heating the latter with ammonia provided a novel synthesis of γ-carbolines.Condensation of 1,2-dimethyl-3-formyl-5-nitroindole with dimethylacetamide diethyl acetal gave 2-dimethylamino-6-nitro-9-methylcarbazole.

1H-INDOLE-3-ACETAMIDE SPLA2 INHIBITORS

A class of novel 1-indole-3-acetamides represented by the formula; is disclosed together with the use of such indole compounds for inhibiting sPLA2 mediated release of fatty acids.