120658-71-1

Basic information

• Product Name: 2-OXO-3-(4-(TRIFLUOROMETHYL)PHENYL)PROPANOIC ACID
• Synonyms: 2-OXO-3-(4-(TRIFLUOROMETHYL)PHENYL)PROPANOIC ACID
• CAS NO: 120658-71-1
• Molecular Formula: C₁₀H₇F₃O₃
• Molecular Weight: 232.16
• Mol File: 120658-71-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-OXO-3-(4-(TRIFLUOROMETHYL)PHENYL)PROPANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-OXO-3-(4-(TRIFLUOROMETHYL)PHENYL)PROPANOIC ACID(120658-71-1)
• EPA Substance Registry System: 2-OXO-3-(4-(TRIFLUOROMETHYL)PHENYL)PROPANOIC ACID(120658-71-1)

Safety Data

• Hazardous Substances Data: 120658-71-1(Hazardous Substances Data)

Usage

General Description

2-OXO-3-(4-(TRIFLUOROMETHYL)PHENYL)PROPANOIC ACID, also known as fenofibric acid, is a medication used to reduce cholesterol levels in the blood. It belongs to the class of fibrates and works by increasing the breakdown of fatty acids and decreasing the production of triglycerides in the liver. Fenofibric acid is also used to treat high triglyceride levels and mixed dyslipidemia. It is typically taken orally as a tablet and is often prescribed in combination with a healthy diet and exercise. Side effects may include stomach pain, nausea, and headache. Additionally, fenofibric acid may interact with certain medications, so it is important to consult a healthcare professional before use.

Upstream product

• 3094-34-6 2-acetamido-3-(4-(trifluoromethyl)phenyl)acrylic acid 
• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 543-24-8 N-acetylglycine 
• 3832-75-5 (S)-4-trifluoromethylphenylalanine 
• 16642-92-5 4-(trifluoromethyl)cinnamic acid 

Downstream Products

• 14091-16-8 4-(trifluoromethyl)-dl-phenylalanine 
• 80980-59-2 racemic 15-formyl-14-hydroxy-5,5-dimethyl-2,8-dithia<9>(2,5)pyridinophane 
• 1567951-67-0 C₁₉H₁₄F₃NO₃ 
• 1627500-60-0 (Z)-2-(1,1-di-chloropentyl)-5-(4-(trifluoromethyl)benzylidene)oxazolidin-4-one 
• 1627500-61-1 (Z)-1-(3-(4-oxo-5-(4-(trifluoromethyl)benzylidene)oxazolidin-2-yl)propyl)guanidine 
• 1627500-64-4 2-oxo-3-(4-(trifluoromethyl)phenyl)propanoyl chloride 

Relevant articles and documents

Synthesis of D- and L-Phenylalanine Derivatives by Phenylalanine Ammonia Lyases: A Multienzymatic Cascade Process

The synthesis of substituted D-phenylalanines in high yield and excellent optical purity, starting from inexpensive cinnamic acids, has been achieved with a novel one-pot approach by coupling phenylalanine ammonia lyase (PAL) amination with a chemoenzymatic deracemization (based on stereoselective oxidation and nonselective reduction). A simple high-throughput solid-phase screening method has also been developed to identify PALs with higher rates of formation of non-natural D-phenylalanines. The best variants were exploited in the chemoenzymatic cascade, thus increasing the yield and ee value of the D-configured product. Furthermore, the system was extended to the preparation of those L-phenylalanines which are obtained with a low ee value using PAL amination.

Asymmetric synthesis of fluorophenylalanines and (trifluoromethyl)phenylalanines; the use of chiral pyridoxamine-like pyridinophane-zinc complex as an enzyme mimic

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