120710-95-4

Basic information

• Product Name: (S)-2-chloro-3-phenylpropanoic acid chloride
• Synonyms: (S)-2-chloro-3-phenylpropanoic acid chloride
• CAS NO: 120710-95-4
• Molecular Weight: 203.068
• Mol File: 120710-95-4.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: (S)-2-chloro-3-phenylpropanoic acid chloride(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-chloro-3-phenylpropanoic acid chloride(120710-95-4)
• EPA Substance Registry System: (S)-2-chloro-3-phenylpropanoic acid chloride(120710-95-4)

Safety Data

• Hazardous Substances Data: 120710-95-4(Hazardous Substances Data)

Upstream product

• 501-52-0 3-Phenylpropionic acid 
• 828-01-3 phenyllactic acid 
• 63-91-2 L-phenylalanine 
• 27172-85-6 phenylalanine methyl ester hydrochloride 
• 4530-18-1 2-(tert-butoxycarbonylamino)-3-phenylpropionic acid 
• 16503-53-0 2-bromo-3-phenylpropanoic acid 
• 150-30-1 Phenylalanine 
• 7474-06-8 2-chloro-3-phenylpropionic acid 
• 7474-06-8 (S)-2-chloro-3-phenyl-propionic acid 

Downstream Products

• 1330781-99-1 6-(5-methyl-1H-pyrazol-4-yl)-2-(2-phenyl-1-pyrrolidin-1-ylethyl)thieno[3,2-d]pyrimidin-4(3H)-one 
• 20334-86-5 N-phenyl-2-chloro-3-phenylpropanamide 
• 6632-27-5 2-chloro-N-(3-nitrophenyl)-3-phenylpropanamide 
• 59200-36-1 methyl (S)-2-chloro-3-phenylpropanoate 
• 274902-15-7 (S)-2-Chloro-3-phenyl-propionic acid 4-nitro-phenyl ester 
• 274902-20-4 2-chloro-N,N-dimethyl-3-phenyl-propionamide 
• 274902-22-6 diisopropyl (S)-2-chloro-3-phenylpropanamide 
• 274902-17-9 phenyl (S)-2-chloro-3-phenylpropanamide 
• 274902-16-8 2-chloro-N-methyl-3-phenyl-propionamide 
• 274902-21-5 2-chloro-N-methyl-3,N-diphenyl-propionamide 
• 274902-14-6 (S)-2-Chloro-3-phenyl-propionic acid phenyl ester 
• 408504-89-2 (2R,3S)-3-bromo-2-chloro-3-phenylpropanoic acid chloride 
• 1599459-88-7 (2'S)-4-chloro-2-(2'-chloro-3'-phenylpropanamido)benzoic acid 
• 1599459-85-4 (2'S)-5-bromo-2-(2'-chloro-3'-phenylpropanamido)benzoic acid 

Relevant articles and documents

Stereoselective synthesis of (3r)-3-alkyl-4,1-benzoxazepine-2,5-diones

Novel 3-alkyl-4,1-benzoxazepine-2,5-diones were synthesized in good ee exploiting the chiral pool methodology, an economical way of asymmetric synthesis. Various anthranilic acids are coupled with different α-haloacids to afford N-acylated anthranilic aci

Synthesis and anti-parasitic activity of C-benzylated (N-arylcarbamoyl)alkylphosphonate esters

Unexpected substituent-dependent regioselectivty challenges in the synthesis of C-benzylated (N-arylcarbamoyl)phosphonate esters have been resolved. The C-benzylated N-furfurylcarbamoyl derivative showed low micromolar PfLDH inhibition, while one of the C-benzylated N-arylcarbamoyl analogues was active against Nagana Trypanosoma brucei parasites which are responsible for African trypanosomiasis in cattle.

Chiron based synthesis of isocoumarins: Reactivity of α-substituted carboxylic acids

The asymmetric synthesis of a novel (S)-isocoumarin has been attempted in a single step by the coupling of homophthalic acid with (S)-N-protected amino acids and α-chloroacids at high temperature by exploiting a chiral pool methodology. The coupling of homophthalic acid with N-protected (S)-amino acids gave exclusion of the carboxyl/alkyl group. However, coupling of homophthalic acid with α-chloroacids afforded asymmetric isocoumarins in high yield.