1207262-57-4

Basic information

• Product Name: 2-(5-{4-[cyclohexy(methyl)carbamoyl]piperazin-1-yl}-1,2,4-oxadiazol-3-yl)-1-methyl-1H-3,1-benzimidazol-3-ium trifluoroacetate
• Synonyms: 2-(5-{4-[cyclohexy(methyl)carbamoyl]piperazin-1-yl}-1,2,4-oxadiazol-3-yl)-1-methyl-1H-3,1-benzimidazol-3-ium trifluoroacetate
• CAS NO: 1207262-57-4
• Molecular Weight: 537.542
• Mol File: 1207262-57-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(5-{4-[cyclohexy(methyl)carbamoyl]piperazin-1-yl}-1,2,4-oxadiazol-3-yl)-1-methyl-1H-3,1-benzimidazol-3-ium trifluoroacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-{4-[cyclohexy(methyl)carbamoyl]piperazin-1-yl}-1,2,4-oxadiazol-3-yl)-1-methyl-1H-3,1-benzimidazol-3-ium trifluoroacetate(1207262-57-4)
• EPA Substance Registry System: 2-(5-{4-[cyclohexy(methyl)carbamoyl]piperazin-1-yl}-1,2,4-oxadiazol-3-yl)-1-methyl-1H-3,1-benzimidazol-3-ium trifluoroacetate(1207262-57-4)

Safety Data

• Hazardous Substances Data: 1207262-57-4(Hazardous Substances Data)

Upstream product

• 35028-38-7 N-methyl-N-cyclohexylaminocarbonyl chloride 

Relevant articles and documents

1,2,4-OXADIAZOLE SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES AS SMO ANTAGONISTS

The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts, stereoisomers or tautomers thereof which are inhibitors of the Sonic Hedgehog pathway, in particular Smo antagonists. Thus the compounds of this invention are useful for the treatment of diseases associated with abnormal hedgehog pathway activation, including cancer, for example basal cell carcinoma, medulloblastoma, prostate, pancreatic, breast, colon, bone and small cell lung cancers, and cancers of the upper GI tract.