1207449-70-4

Basic information

• Product Name: C₂₈H₂₇ClN₈
• CAS NO: 1207449-70-4
• Molecular Weight: 511.029
• Mol File: 1207449-70-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₈H₂₇ClN₈(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₈H₂₇ClN₈(1207449-70-4)
• EPA Substance Registry System: C₂₈H₂₇ClN₈(1207449-70-4)

Safety Data

• Hazardous Substances Data: 1207449-70-4(Hazardous Substances Data)

Upstream product

• 1973-09-7 6-chloro-N,N'-diphenyl-1,3,5-triazine-2,4-diamine 
• 53186-45-1 N₁-(7-chloroquinolin-4-yl)butane-1,4-diamine 

Relevant articles and documents

Synthesis, antimalarial activity and cytotoxicity of 4-aminoquinoline-triazine conjugates

A series of 4-aminoquinoline-triazine conjugates with different substitution pattern have been synthesized and evaluated for their in vitro antimalarial activity against chloroquine-sensitive and resistant strains of Plasmodium falciparum. Compounds 16, 19, 28 and 35 exhibited promising antimalarial activity against both strains of P. falciparum. Cytotoxicity of these compounds was tested against three cell lines. Several compounds did not show any cytotoxicity up to a high concentration (48 μM), others exhibited mild toxicities but selective index for antimalarial activity was high for most of these conjugates.