1208-10-2

Basic information

• Product Name: [2-(2-methoxyphenyl)hydrazinylidene]propanedinitrile
• Synonyms: [(2-Methoxyphenyl)hydrazono]malononitrile; propanedinitrile, 2-[2-(2-methoxyphenyl)hydrazinylidene]-
• CAS NO: 1208-10-2
• Molecular Formula: C₁₀H₈N₄O
• Molecular Weight: 200.1967
• Mol File: 1208-10-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 328.7°C at 760 mmHg
• Flash Point: 152.6°C
• Density: 1.15g/cm³
• Vapor Pressure: 0.000186mmHg at 25°C
• Refractive Index: 1.572
• CAS DataBase Reference: [2-(2-methoxyphenyl)hydrazinylidene]propanedinitrile(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(2-methoxyphenyl)hydrazinylidene]propanedinitrile(1208-10-2)
• EPA Substance Registry System: [2-(2-methoxyphenyl)hydrazinylidene]propanedinitrile(1208-10-2)

Safety Data

• Hazardous Substances Data: 1208-10-2(Hazardous Substances Data)

Upstream product

• 90-04-0 2-methoxy-phenylamine 
• 109-77-3 malononitrile 
• 922-64-5 1,1-dicyanoethylene 

Downstream Products

• 1149376-78-2 2-methoxyphenylhydrazono-1H-tetrazol-5-yl-acetonitrile 

Relevant articles and documents

COMPOUNDS HAVING PSEUDOMONAS ANTI-BIOFILM PROPERTIES

The present invention relates to c-di-GMP lowering chemical compounds having anti- biofilm properties. In particular, the present invention relates to anti-biofilm compounds or salts or tautomers thereof for use in treatment and/or prevention of bacterial biofilm infection in human subjects caused by biofilm-forming bacteria of the genus Pseudomonas, in particular Pseudomonas spp. including P. aeruginosa. Methods of treating such infections in human subjects are contemplated as well. The present inventions further relates to the use of an anti-biofilm compound or a salt or tautomer thereof for dispersing biofilms in industrial water systems.

SAR study of 4-arylazo-3,5-diamino-1: H -pyrazoles: identification of small molecules that induce dispersal of Pseudomonas aeruginosa biofilms

By screening of a collection of 50 000 small-molecule compounds, we recently identified 4-arylazo-3,5-diamino-1H-pyrazoles as a novel group of anti-biofilm agents. Here, we report a SAR study based on 60 analogues by examining ways in which the pharmacoph

Synthesis and antimicrobial activity studies of some novel substituted phenylhydrazono-1H-tetrazol-5-ylacetonitriles

In this study, some substituted phenylhydrazono-1H-tetrazol-5-yl- acetonitriles have been synthesized (2a-o, 2a and 2k are known compounds). The synthesized compounds were characterized by spectroscopic methods [Fourier-transform infrared (FTIR), nuclear magnetic resonance (NMR), mass spectroscopy (MS)]. In addition, antimicrobial activities of synthesized compounds were investigated against Bacillus cereus RSKK 863, Escherichia coli ATCC 3521, Pseudomonas aeruginosa ATCC 2921, and Staphylococcus aureus TP32. These compounds had antimicrobial effect against these bacteria (except for 21). Birkhaeuser Boston 2009.