120800-90-0Relevant articles and documents
Preparation method of chiral morpholine compound
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, (2018/10/11)
The invention provides a preparation method of a chiral morpholine compound. With chiral ethylene oxide as a raw material, the preparation method comprises the steps of ring opening, cyclization and deprotection reaction to obtain the chiral 2-substituted morpholine compound. The preparation process is simple and environmentally friendly, has mild reaction conditions, is free of irritation or allergens, has higher total yield and good safety and is suitable for industrial amplification.
COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS
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Page/Page column 39-40, (2008/12/07)
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Synthesis and Reaction of Optically Active Morpholinones
Kashima, Choji,Harada, Kazuo
, p. 1521 - 1526 (2007/10/02)
The reactions of variously substituted chiral morpholin-2-and-3-ones chemoselectively synthesized from chiral amino acids and lactic acid as the chiral source are described.