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1208222-41-6

1208222-41-6

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1208222-41-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1208222-41-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,8,2,2 and 2 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1208222-41:
(9*1)+(8*2)+(7*0)+(6*8)+(5*2)+(4*2)+(3*2)+(2*4)+(1*1)=106
106 % 10 = 6
So 1208222-41-6 is a valid CAS Registry Number.

1208222-41-6Downstream Products

1208222-41-6Relevant articles and documents

Chemical lead optimization of a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM) lead. Part I: Development of the first highly selective M5 PAM

Bridges, Thomas M.,Kennedy, J. Phillip,Cho, Hyekyung P.,Breininger, Micah L.,Gentry, Patrick R.,Hopkins, Corey R.,Conn, P. Jeffrey,Lindsley, Craig W.

scheme or table, p. 558 - 562 (2010/08/06)

This Letter describes a chemical lead optimization campaign directed at VU0238429, the first M5-preferring positive allosteric modulator (PAM), discovered through analog work around VU0119498, a pan Gq mAChR M1, M3, M5 PAM. An iterative library synthesis approach delivered the first selective M5 PAM (no activity at M1-M4 @ 30 μM), and an important tool compound to study the role of M5 in the CNS.

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