121006-57-3

Basic information

• Product Name: 5-Methoxy-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester
• CAS NO: 121006-57-3
• Molecular Weight: 263.337
• Mol File: 121006-57-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Methoxy-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methoxy-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester(121006-57-3)
• EPA Substance Registry System: 5-Methoxy-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester(121006-57-3)

Safety Data

• Hazardous Substances Data: 121006-57-3(Hazardous Substances Data)

Upstream product

• 6940-76-7 1-iodo-3-chloro-propane 
• 60144-52-7 tert-butyl 3-methoxyphenylcarbamate 

Relevant articles and documents

SYNTHESIS OF 1,2,3,4-TETRAHYDROQUINOLINES AND 1,2,3,4-TETRAHYDRO-1,6-NAPHTHYRIDINES BY A DIRECTED LITHIATION REACTION

N-(tert-butoxycarbonyl)anilines (7), are easily converted in a one pot reaction sequence into the N-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroquinolines (8), by directed ortho lithiation followed by reaction with 1-chloro-3-iodopropane, hence providing a new versatile quinoline ring nucleus synthesis.In an analogous reaction 2-N-(tert-butoxycarbonyl)- and an 2-N-(pivaloylamino)pyridine are converted to 1,2,3,4-tetrahydro-1,6-naphthyridines.