121077-68-7

Basic information

• Product Name: Arsonium, (3-methyl-2-oxobutyl)triphenyl-, bromide
• CAS NO: 121077-68-7
• Molecular Formula: C23H24AsO.Br
• Molecular Weight: 471.269
• Mol File: 121077-68-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Arsonium, (3-methyl-2-oxobutyl)triphenyl-, bromide(CAS DataBase Reference)
• NIST Chemistry Reference: Arsonium, (3-methyl-2-oxobutyl)triphenyl-, bromide(121077-68-7)
• EPA Substance Registry System: Arsonium, (3-methyl-2-oxobutyl)triphenyl-, bromide(121077-68-7)

Safety Data

• Hazardous Substances Data: 121077-68-7(Hazardous Substances Data)

Upstream product

• 603-32-7 triphenyl-arsane 
• 19967-55-6 1-bromo-3-methyl-2-butanone 

Downstream Products

• 474-63-5 24-methylene cholesterol 
• 67962-14-5 (E)-1-(4-methoxyphenyl)-4-methylpent-1-en-3-one 
• 3160-32-5 (1E)-4-methyl-1-phenylpent-1-en-3-one 
• 86983-92-8 (E)-4-methyl-1-(p-nitrophenyl)-1-penten-3-one 

Relevant articles and documents

Synthesis of polyhydroxysterols (I): Synthesis of 24-methylenecholest-4-en-3β,6β-diol, a cytotoxic natural hydroxylated sterol

Starting from stigmasterol (2), 24-methylenecholest-4-en-3β,6β-diol (1), a cytotoxic natural dihydroxylated sterol, was synthesized via 10 steps in 20% overall yield. The introduction of a side-chain of sterol was achieved by solid-liquid phase-transfer Wittig reaction using (3-methyl-2-oxo)butyltriphenylarsonium bromide (12) and K2CO3. Construction of the steroidal nucleus was finished by the addition of 3β-acetoxycholest-5,6-en-24-one (7) with NBA in dioxane under ambient temperature and by the elimination of 3β, 6β-diacetoxy-5a-bromocholestane-24-one (9). The spectral data of the synthetic product (1) are completely consistent with those of the natural compound (1). Copyright (C) 2001 Elsevier Science Inc.