121149-53-9Relevant articles and documents
A One Step Synthesis of 4-Substituted Imidazoles. An Important Observation When N-Alkylating Imidazoles
Whitten, Jeffrey P.,Matthews, Donald P.,McCarthy, James R.,Barbuch, Robert J.
, p. 1845 - 1847 (2007/10/02)
Imidazoles substituted in the 2-position with methyl, 1e, phenyl, 1a, 2-imidazole, 1b-d, or t-butyldiphenylsilyl, 1f, react with soft electrophiles 2 to give modest yields of 4(5)-C-alkylated-imidazoles 3 and N-alkylated products 5.These two products are readily separated by flash chromatography.