121169-22-0

Basic information

• Product Name: 1,1'-Biphenyl, 2,2'-bis(methoxymethoxy)-
• CAS NO: 121169-22-0
• Molecular Formula: C16H18O4
• Molecular Weight: 274.317
• Mol File: 121169-22-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,1'-Biphenyl, 2,2'-bis(methoxymethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1'-Biphenyl, 2,2'-bis(methoxymethoxy)-(121169-22-0)
• EPA Substance Registry System: 1,1'-Biphenyl, 2,2'-bis(methoxymethoxy)-(121169-22-0)

Safety Data

• Hazardous Substances Data: 121169-22-0(Hazardous Substances Data)

Upstream product

• 28113-30-6 Dibromo-2,3-crotonsaeureethylester 
• 176246-52-9 methyl (E)-2,3-dibromo-2-octenoate 
• 176246-53-0 ethyl (E)-2,3-dibromo-2-phenylpropenoate 
• 824-91-9 O-methoxymethylphenol 
• 108-24-7 acetic anhydride 

Downstream Products

• 1612873-17-2 [1,1'-biphenyl]-2,2'-diol-3,3'-bis({[2,6-bis(methyl)phenyl]imino}methyl) 

Relevant articles and documents

Palladium-mediated cross-coupling reactions involving 3-substituted alkyl (E)-2,3-dibromopropenoates and arylzinc or aryltin derivatives

Stereodefined unsymmetrically 3,3-disubstituted alkyl 2-bromopropenoates, 5, were regioselectively prepared by Pd-mediated reactions between 3-alkyl, 3-aryl and 3-alkoxycarbonyl substituted (E)-2,3-dibromopropenoates, (E)-7, and aryl or 1-alkynylzinc chlorides. The stereospecificity of these reactions was found to be dependent on the type of substituent present in the 3-position of (E)-7. The (E)-stereochemistry of compounds 5b, 5d and 5i so prepared was confirmed by their conversion into the corresponding 4-substituted 3-bromocoumarins. Tetrasubstituted α,β-unsaturated esters 10 were then synthesized by Pd-mediated reactions either of (E)-7 with a molar excess of an arylzinc chloride or an aryltributylstannane, or of a compound of general formula 5 with an aryltributylstannane. An examination of the parameters which influence the stereochemistry and the yields of these arylations was made.