121195-60-6

Basic information

• Product Name: 1H-Indole-2,3-dicarboxylic acid, 1-(phenylmethyl)-
• CAS NO: 121195-60-6
• Molecular Formula: C17H13NO4
• Molecular Weight: 295.295
• Mol File: 121195-60-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Indole-2,3-dicarboxylic acid, 1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-2,3-dicarboxylic acid, 1-(phenylmethyl)-(121195-60-6)
• EPA Substance Registry System: 1H-Indole-2,3-dicarboxylic acid, 1-(phenylmethyl)-(121195-60-6)

Safety Data

• Hazardous Substances Data: 121195-60-6(Hazardous Substances Data)

Upstream product

• 614-31-3 N-benzyl-N-phenylhydrazine 
• 54781-93-0 1H-indole-2,3-dicarboxylic acid dimethyl ester 
• 100-39-0 benzyl bromide 
• 103030-09-7 indole-2,3-dicarboxylic acid 
• 1217-89-6 1-benzylisatin 
• 105-39-5 chloroacetic acid ethyl ester 
• 857809-56-4 dimethyl 1-benzylindole-2,3-dicarboxylate 

Downstream Products

• 192991-46-1 1-Benzyl-2-(2,2-dimethyl-propionyl)-1H-indole-3-carboxylic acid 
• 180902-40-3 1-benzyl-2-benzoylindole-3-carboxylic acid 
• 151054-77-2 1-benzylindole-2,3-dicarboxylic anhydride 
• 17017-71-9 1-benzyl-1H-indole-2-carboxylic acid 
• 3377-71-7 N-benzylindole 

Relevant articles and documents

Reaction of indole-2,3-dicarboxylic anhydride with grignard reagents: synthesis of 2-acylindoles

Reaction of indole-2,3-dicarboxylic anhydride with methylmagnesium bromide and phenylmagnesium bromide gave 2-acetyl- and 2-benzoyl-indole-3-carboxylic acids, but with tert-butylmagnesium chloride, 3-pivaloylindole-2-carboxylic acids were obtained as the main products. Treatment of 2-acylindole-3-carboxylic acids with copper chromite in quinoline or potassium hydroxide gave the corresponding 2-acylindoles.