121238-14-0Relevant articles and documents
SYNTHESIS OF DEOXYCYTIDINE OLIGOMERS CONTAINING PHOSPHORODITHIOATE LINKAGES
Grandas, Ana,Marshall, William S.,Nielsen, John,Caruthers, Marvin H.
, p. 543 - 546 (1989)
Deoxydicytidine phosphoramidite, 4-chlorobenzylmercaptan and tetrazole reacted to form dinucleoside thiophosphite.Oxidation with sulfur yields phosphorodithioates which used to synthesize pentadecadeoxyoligonucleotides containing nuclease resistant phosphorodithioate internucleotide linkages.