121275-51-2Relevant articles and documents
FIVE-MEMBERED 2,3-DIOXOHETEROCYCLES. IX. REACTION OF 5-ARYL-2,3-DIHYDROFURAN-2,3-DIONES WITH AMINO ACIDS
Andreichikov, Yu. S.,Krylova, I. V.
, p. 1995 - 1998 (2007/10/02)
Aliphatic and aromatic amino acids open the ring in 5-aryl-2,3-dihydrofuran-2,3-diones with the formation of the carboxyalkyl- and carboxyphenylamides of aroylpyruvic acids.When heated with thionyl chloride, the products undergo cyclization to 2-aroylacetyl-4H-3,1-benzoxazin-4-ones.