121287-34-1

Basic information

• Product Name: 2,6-bis(methoxymethyloxy)-4-methylbenzaldehyde
• Synonyms: 2,6-bis(methoxymethyloxy)-4-methylbenzaldehyde
• CAS NO: 121287-34-1
• Molecular Weight: 240.256
• Mol File: 121287-34-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2,6-bis(methoxymethyloxy)-4-methylbenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-bis(methoxymethyloxy)-4-methylbenzaldehyde(121287-34-1)
• EPA Substance Registry System: 2,6-bis(methoxymethyloxy)-4-methylbenzaldehyde(121287-34-1)

Safety Data

• Hazardous Substances Data: 121287-34-1(Hazardous Substances Data)

Upstream product

• 504-15-4 orcinol 
• 82265-37-0 1,3-bis(methoxymethoxy)-5-methylbenzene 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 526-37-4 atranol 
• 609-25-6 5-methylpyrogallol 
• 121287-22-7 5-Methyl-2-((2Z,6E)-3,7,11-trimethyl-dodeca-2,6,10-trienyl)-benzene-1,3-diol 
• 121287-15-8 (E)-2-(2,6-Bis-methoxymethoxy-4-methyl-benzyl)-3-hydroxy-3,7,11-trimethyl-dodeca-6,10-dienoic acid 
• 121287-16-9 1,3-Bis-methoxymethoxy-5-methyl-2-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-trienyl)-benzene 
• 121287-18-1 <2,6-bis(methoxymethyloxy)-4-methylphenyl>propionic acid 
• 6903-07-7 grifolin 
• 121287-17-0 (E)-3-<2,6-bis(methoxymethyloxy)-4-methylphenyl>acrylic acid 

Relevant articles and documents

Exploitation of co-operative directed ortho-metallation (DoM) by 1,3-related -omom groups in the development of a fully regio-controlled synthesis of atranol from orcinol

-

Yicathins B and C and Analogues: Total Synthesis, Lipophilicity and Biological Activities

Natural products have always been an important source of new hits and leads in drug discovery, with the marine environment being regarded as a significant source of novel and exquisite bioactive compounds. Yicathins B and C are two marine-derived xanthones that have shown antibacterial and antifungal activity. Herein, the total synthesis of these yicathins and six novel analogues is reported for the first time. As marine natural products tend to have very lipophilic scaffolds, the lipophilicity of yicathins and their analogues was evaluated in the classical octanol/water system and a biomimetic model-based system. As the xanthonic nucleus is a “privileged structure”, other biological activities were evaluated, namely antitumor and anti-inflammatory activities. An interesting anti-inflammatory activity was identified for yicathin analogues that paves the way for the design of dual activity (anti-infective and anti-inflammatory) marine-inspired xanthone derivatives.