121290-83-3Relevant articles and documents
Sterol compound and its pharmaceutically acceptable salt or prodrug, and application thereof
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Paragraph 0178; 0185-0187; 0190, (2019/10/01)
The present invention discloses a sterol compound and its pharmaceutically acceptable salt or prodrug, and an application thereof in the prevention or treatment of malignant tumors associated with LXR. The compound has an inhibitory ability against various malignant tumors in in-vitro experiments, and also has an inhibitory ability against malignant tumors malignant tumors in in-vivo experiments.The sterol skeleton compound has the equivalent curative effect on the malignant tumors with cytotoxic drugs currently used for treating the tumors, and has the same therapeutic effect with positive drugs for evaluating the drug effect of the compound. The compound has the advantages of good antitumor activity, good safety, no side effects caused by the positive drugs, and facilitation of enhancement of the immune function of animals. The sterol compound has a potential to become a safe and effective broad-spectrum antitumor drug.