121331-23-5Relevant articles and documents
Desymmetrization of prochiral anhydrides with Evans' oxazolidinones: An efficient route to homochiral glutaric and adipic acid derivatives
Verma, Rekha,Mithran, Seturam,Ghosh, Sunil K.
, p. 257 - 264 (2007/10/03)
The prochiral recognition between enantiotopic carbonyl groups in the reaction of 3-substituted glutaric and 3,4-disubstituted adipic anhydrides with anions of Evans' oxazolidinones has been investigated. Each of the σ-symmetric anhydrides provided a diastereoisomeric mixture of half-acids which were separated either by fractional crystallization or by column chromatography of their esters. The diastereoselectivity of the desymmetrization reaction is dependent on the substituents present in the anhydrides.
Practical Synthesis of an Enantiomerically Pure Synthon for the Preparation of Mevinic Acid Analogues
Karanewsky, Donald S.,Malley, Mary F.,Gougoutas, Jack Z.
, p. 3744 - 3747 (2007/10/02)
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