121349-16-4Relevant articles and documents
OCTATHYMIDYLATES INVOLVING ALTERNATING NEOPENTYLPHOSPHOTHIONOTRIESTER-PHOSPHODIESTER LINKAGES WITH CONTROLLED STEREOCHEMISTRY AT THE MODIFIED P-CENTER
Hau, J. F.,Asseline, U.,Thuong, N. T.
, p. 2497 - 2498 (2007/10/02)
Starting from each pure stereoisomer of neopentylphosphothionotriester dimer, octathymidylates involving alternating stereoregular neopentylphosphothionotriester-phosphodiester linkages and covalently linked to an acridine derivative at their 3'-end have been synthesized.Their stability towards nuclease degradation was studied by comparison with an octanucleotide-acridine conjugate containing only phosphodiester groups.