1213611-52-9

Basic information

• Product Name: 9-bromo-5-(3,4-dichlorobenzyl)-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one
• CAS NO: 1213611-52-9
• Molecular Weight: 486.195
• Mol File: 1213611-52-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 9-bromo-5-(3,4-dichlorobenzyl)-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 9-bromo-5-(3,4-dichlorobenzyl)-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one(1213611-52-9)
• EPA Substance Registry System: 9-bromo-5-(3,4-dichlorobenzyl)-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one(1213611-52-9)

Safety Data

• Hazardous Substances Data: 1213611-52-9(Hazardous Substances Data)

Upstream product

• 142273-20-9 kenpaullone 
• 18880-04-1 3,4-dichlorobenzyl bromide 

Relevant articles and documents

Development of 5-benzylpaullones and paullone-9-carboxylic acid alkyl esters as selective inhibitors of mitochondrial malate dehydrogenase (mMDH)

A collection of paullones was tested for inhibitory activity against mitochondrial malate dehydrogenase (mMDH) as a biological target for antiproliferative activity. Based on the results of this screening, 5-benzylpaullones and paullone-9-carboxylic acid alkyl esters were developed as selective mMDH inhibitors. The new derivatives did not show noteworthy antiproliferative activity when tested on a panel of cancer cell lines, suggesting that mMDH inhibition is of minor relevance for the growth inhibition caused by paullones.