121370-56-7

Basic information

• Product Name: 4-(9H-Purin-6-yl)-piperazine-1-carboxylic acid tert-butyl ester
• Synonyms: 4-(9H-Purin-6-yl)-piperazine-1-carboxylic acid tert-butyl ester;1-Piperazinecarboxylic acid, 4-(9H-purin-6-yl)-, 1,1-diMethylethyl ester;tert-Butyl 4-(9H-purin-6-yl)piperazine-1-carboxylate;4-(1H-Purin-6-yl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
• CAS NO: 121370-56-7
• Molecular Formula: C₁₄H₂₀N₆O₂
• Molecular Weight: 304.35
• Product Categories: pharmacetical
• Mol File: 121370-56-7.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 545.4°Cat760mmHg
• Flash Point: 283.6°C
• Appearance: /
• Density: 1.311g/cm³
• Vapor Pressure: 5.94E-12mmHg at 25°C
• Refractive Index: 1.618
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-(9H-Purin-6-yl)-piperazine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(9H-Purin-6-yl)-piperazine-1-carboxylic acid tert-butyl ester(121370-56-7)
• EPA Substance Registry System: 4-(9H-Purin-6-yl)-piperazine-1-carboxylic acid tert-butyl ester(121370-56-7)

Safety Data

• Hazardous Substances Data: 121370-56-7(Hazardous Substances Data)

Usage

General Description

The chemical 4-(9H-Purin-6-yl)-piperazine-1-carboxylic acid tert-butyl ester, also known as TIPPPE, is a tert-butyl ester derivative of the purine compound 4-(9H-Purin-6-yl)-piperazine-1-carboxylic acid. It is a synthetic compound with potential therapeutic applications, particularly in the field of medicinal chemistry and drug development. TIPPPE has been studied for its potential as a modulator of purinergic receptors, which play a role in various physiological and pathological processes. Additionally, TIPPPE has shown promise in preclinical studies as a potential anti-inflammatory and anti-neuroinflammatory agent. Its chemical structure and properties make it an interesting target for further research and potential drug discovery.

InChI:InChI=1/C14H20N6O2/c1-14(2,3)22-13(21)20-6-4-19(5-7-20)12-10-11(16-8-15-10)17-9-18-12/h8-9H,4-7H2,1-3H3,(H,15,16,17,18)

Upstream product

• 87-42-3 6-chloropurine 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 121370-62-5 tert-butyl 4-(5,6-diaminopyrimidin-4-yl)piperazine-1-carboxylate 
• 149-73-5 trimethyl orthoformate 
• 245450-04-8 4-(6-amino-5-nitro-4-pyrimidinyl)-1-piperazinecarboxylic acid tert-butyl ester 

Downstream Products

• 705300-81-8 4-[9-(2-Cyanobenzyl)-9H-purin-6-yl]-piperazine-1-carboxylic acid t-butyl ester 
• 245449-24-5 N-(4-Nitrophenyl)-4-(6-purinyl)-1-piperazinecarboxamide 

Relevant articles and documents

1-methylpurine-4-methyleneandrostane-triazole derivative, synthesis method and application thereof

The invention belongs to the technical field of medicinal chemistry, and relates to a 1- methylpurine-4- methyleneandrostane-triazole derivative with anticancer activity. The compound has the generalformula as shown in the specification. The derivative of the invention is prepared by using a 6-chloropurine compound as a raw material and through nucleophilic reaction, halogenation, azidation, cycloaddition and a Claisen-Schmidt condensation reaction. The preparation method is simple and the conditions are mild. These compounds have obvious inhibitory effects on cell lines such as gastric cancer and prostate cancer, can be used for preparing antitumor drugs, and provide a lead compound structure for further research on anticancer drugs.

Piperazinone compound containing piperidine ring and preparation method and application thereof

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Pd/PTABS: Catalyst for Room Temperature Amination of Heteroarenes

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