121384-01-8

Basic information

• Product Name: Acetic acid (R)-furan-2-yl-phenyl-methyl ester
• Synonyms: Acetic acid (R)-furan-2-yl-phenyl-methyl ester
• CAS NO: 121384-01-8
• Molecular Weight: 216.236
• Mol File: 121384-01-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid (R)-furan-2-yl-phenyl-methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid (R)-furan-2-yl-phenyl-methyl ester(121384-01-8)
• EPA Substance Registry System: Acetic acid (R)-furan-2-yl-phenyl-methyl ester(121384-01-8)

Safety Data

• Hazardous Substances Data: 121384-01-8(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 113565-51-8 (R)-2-furylphenylmethanol 
• 60907-91-7 2-furyl(phenyl)methanol 

Downstream Products

• 51019-43-3 (R)-(-)-O-acetylmandelic acid 

Relevant articles and documents

Preparation of Optically Active 2-Furylcarbinols by Kinetic Resolution Using the Sharpless Reagent and Their Application in Organic Synthesis

The kinetic resolution of 2-furylcarbinols 1 by the Sharpless reagent proceeds highly efficiently, thus providing a general method for the synthesis of homochiral 1.The reaction can be applied to compounds 1 possessing various types of substituents, although compound 1d, which has a sterically demanding tertiary alkyl group, is a poor substrate.The kinetic resolution of 3-furylcarbinol 3 also proceeds efficiently.Various homochiral 1 thus obtained have been successfully converted into α-alkoxy acids 4 by oxidative cleavage of the furan ring after protection of the hydroxyl group.The compound (R)-1b has been converted into the naturally occuring γ-lactone 5.