1214-98-8

Basic information

• Product Name: (1S,2R)-2-Methoxymethyl-cyclopentylamine
• Synonyms: (1S,2R)-2-Methoxymethyl-cyclopentylamine
• CAS NO: 1214-98-8
• Molecular Weight: 0
• Mol File: 1214-98-8.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: (1S,2R)-2-Methoxymethyl-cyclopentylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R)-2-Methoxymethyl-cyclopentylamine(1214-98-8)
• EPA Substance Registry System: (1S,2R)-2-Methoxymethyl-cyclopentylamine(1214-98-8)

Safety Data

• Hazardous Substances Data: 1214-98-8(Hazardous Substances Data)

Usage

Description

(1S,2R)-2-Methoxymethyl-cyclopentylamine is a chiral chemical compound with the molecular formula C8H17NO. It features an amine group attached to a cyclopentyl ring, with a methoxymethyl group connected to the second carbon atom. As a chiral molecule, it exists in two enantiomers, (1S,2R) and (1R,2S). (1S,2R)-2-Methoxymethyl-cyclopentylamine is widely utilized in the synthesis of pharmaceuticals and other organic compounds due to its unique structure and properties, making it a versatile chemical for applications in medicine, agriculture, and material science. However, it is crucial to handle this compound with care due to its potential toxicity and reactivity.

Uses

Used in Pharmaceutical Synthesis:
(1S,2R)-2-Methoxymethyl-cyclopentylamine is used as a key intermediate in the synthesis of various pharmaceuticals for its unique structural features and reactivity. Its ability to form stable derivatives and participate in a range of chemical reactions makes it a valuable component in drug development.
Used in Organic Chemistry:
In the field of organic chemistry, (1S,2R)-2-Methoxymethyl-cyclopentylamine is used as a versatile building block for the creation of complex organic compounds. Its cyclopentyl ring and methoxymethyl group provide a foundation for further functionalization and the development of novel molecules with specific properties.
Used in Material Science:
(1S,2R)-2-Methoxymethyl-cyclopentylamine is employed in material science for its potential to contribute to the development of new materials with unique properties. Its structural characteristics can be leveraged to create materials with enhanced performance in various applications, such as coatings, adhesives, or polymers.
Used in Agriculture:
In agricultural applications, (1S,2R)-2-Methoxymethyl-cyclopentylamine may be used as a precursor for the development of new agrochemicals, such as pesticides or herbicides. Its reactivity and structural features can be harnessed to create compounds that effectively target specific pests or weeds while minimizing environmental impact.

Upstream product

• 940006-58-6 S-phenyl 2-O-acetyl-4-O-benzyl-3-O-(4-methoxybenzyl)-α-L-thiorhamnopyranoside 
• 108-98-5 thiophenol 
• 51921-33-6 1,2,3,4-tetra-O-acetyl-D-fucopyranose 
• 141193-62-6 Phenyl-2,3,4-tri-O-acetyl-6-desoxy-1-thio-β-D-galactopyranosid 
• 153745-67-6 phenyl 2,3,4-tri-O-acetyl-1-thio-β-L-rhamnopyranoside 
• 883884-80-8 1,2,3,4-tetra-O-acetyl-L-rhamnose 
• 6014-42-2 L-rhamnose 
• 30021-94-4 1,2,3,4-O-tetraacetyl-α-L-rhamnopyranose 
• 7404-35-5 1,2,3,4-tetra-O-acetyl-L-rhamnopyranose 
• 73-34-7 L-rhamnose 
• 3615-41-6 L-Rhamnose 
• 108740-74-5 phenyl 2,3,4-tri-O-acetyl-1-thio-α-L-rhamnopyranoside 

Downstream Products

• 202824-32-6 phenyl (2'R,3'R)-3,4-O-2',3'-dimethoxybutane-2',3'-diyl-1-thio-α-L-rhamnopyranoside 
• 108740-74-5 phenyl 2,3,4-tri-O-acetyl-1-thio-α-L-rhamnopyranoside 
• 940006-51-9 S-phenyl 3-O-(2-naphthylmethyl)-α-L-thiorhamnopyranoside 
• 940006-52-0 S-phenyl 3-O-benzyl-α-L-thiorhamnopyranoside 
• 257936-51-9 phenyl 2-O-benzoyl-6-deoxy-3,4-O-isopropylidene-1-thio-β-D-galactopyranoside 
• 257936-72-4 phenyl 6-deoxy-2,3-di-O-pivaloyl-1-thio-β-D-galactopyranoside 
• 257936-53-1 phenyl 2,3-di-O-benzoyl-6-deoxy-1-thio-β-D-galactopyranoside 
• 257936-74-6 phenyl 4-O-chloroacetyl-6-deoxy-2,3-di-O-pivaloyl-1-thio-β-D-galactopyranoside 
• 257936-58-6 phenyl 2,3-di-O-benzoyl-4-O-chloroacetyl-6-deoxy-1-thio-β-D-galactopyranoside 
• 257936-78-0 methyl O-(6-deoxy-2,3-di-O-pivaloyl-β-D-galactopyranosyl)-(1->4)-O-(2,3,6-tri-O-benzyl-β-D-glucopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside 
• 257936-76-8 methyl O-(4-O-chloroacetyl-6-deoxy-2,3-di-O-pivaloyl-β-D-galactopyranosyl)-(1->4)-O-(2,3,6-tri-O-benzyl-β-D-glucopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside 
• 257936-68-8 methyl O-(6-deoxy-2,3-di-O-pivaloyl-4-O-trifluoromethylsulfonyl-β-D-galactopyranosyl)-(1->4)-O-(2,3,6-tri-O-benzyl-β-D-glucopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside 
• 257936-60-0 methyl O-(2,3-di-O-benzoyl-4-O-chloroacetyl-6-deoxy-β-D-galactopyranosyl)-(1->4)-O-(2,3,6-tri-O-benzyl-β-D-glucopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside 
• 148777-96-2 phenyl 2,3-O-(diphenylmethylene)-1-thio-α-L-rhamnopyranoside 

Relevant articles and documents

Slow glycosylation: Activation of trichloroacetimidates under mild conditions using lithium salts and the role of counterions

Glycosylations were carried out with the two glycosyl donors 4-O-acetyl-2,3-O-isopropylidene-1-O-trichloroacetimidoyl-α-L-rhamnopyranose and 2,3,4-tri-O-benzyl-1-O-trichloro-acetimidoyl-α-L-rhamnopyranose in combination with the two alcohols 1-adamantanol and L-menthol as model glycosyl acceptors. As catalysts, the five lithium salts LiNTf2, LiI, LiClO4, LiPF6 and LiOTf were investigated. We demonstrated that both lithium and the respective counterions are playing a role in the activation of trichloroacetimidate glycosyl donors at rt. Under these very mild conditions, the glycosylations are slow and completed in two to eight days. Depending on the counterion, the rate and yield of the reaction differs; however, the selectivity of all investigated lithium salts is deficient.

A concise synthesis of rhamnan oligosaccharides with alternating α-(1→2)/(1→3)-linkages and repeating α-(1→3)-linkages by iterative α-glycosylation using disaccharide building blocks

A concise synthetic route to rhamnan oligosaccharides with alternating α-(1→2)/(1→3)-linkages and repeating α-(1→3)-linkages is reported. This synthesis was achieved by iterative α-glycosylation using disaccharide building blocks and through orthogonal co

Synthesis of all eight stereoisomeric 6-deoxy-l-hexopyranosyl donors - Trends in using stereoselective reductions or mitsunobu epimerizations

The synthesis of all eight rare but biologically important 6deoxy-L-hexoses as their thioglycoside glycosyl donors starting from the commercially available L-rhamnose or L-fucose is reported. The synthesis of all eight 6-deoxy-L-hexoses was accomplished u