1214922-06-1

Basic information

• Product Name: 5-(iodomethyl)-2-phenyloxazole
• Synonyms: 5-(iodomethyl)-2-phenyloxazole
• CAS NO: 1214922-06-1
• Molecular Weight: 285.084
• Mol File: 1214922-06-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-(iodomethyl)-2-phenyloxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(iodomethyl)-2-phenyloxazole(1214922-06-1)
• EPA Substance Registry System: 5-(iodomethyl)-2-phenyloxazole(1214922-06-1)

Safety Data

• Hazardous Substances Data: 1214922-06-1(Hazardous Substances Data)

Upstream product

• 146896-52-8 2-phenyl-5-methylene-4,5-dihydrooxazole 
• 1464-98-8 N-(prop-2-yn-1-yl)benzamide 

Downstream Products

• 1355332-87-4 2-(2-phenyloxazol-5-yl)acetonitrile 

Relevant articles and documents

Single-Step Synthesis of Iodinated Oxazoles from N-Propargyl Amides Mediated by I2/Iodosylbenzene/Trimethylsilyl Trifluoromethanesulfonate Systems

A combination of I2, iodosylbenzene, and trimethylsilyl trifluoromethanesulfonate (TMSOTf) is effective for single-step synthesis of iodinated oxazoles from N-propargyl amides via the aromatization of the iodocyclized intermediates, which has difficulty proceeding through conventional iodocyclization methods. Compared to the former method consisting of the metal-catalyzed cyclization of N-propargyl amides followed by halogenation of alkylideneoxazolines, the present reaction provides a facile and metal-free procedure.