1215006-12-4

Basic information

• Product Name: N-tert-octyl-N-(((S)-3-(3-fluoro-4-morpholinophenyl)-2-oxazolidin-5-yl)methyl)acetamide
• Synonyms: N-tert-octyl-N-(((S)-3-(3-fluoro-4-morpholinophenyl)-2-oxazolidin-5-yl)methyl)acetamide
• CAS NO: 1215006-12-4
• Molecular Weight: 449.566
• Mol File: 1215006-12-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 582.2±50.0 °C(Predicted)
• Density: 1.153±0.06 g/cm3(Predicted)
• CAS DataBase Reference: N-tert-octyl-N-(((S)-3-(3-fluoro-4-morpholinophenyl)-2-oxazolidin-5-yl)methyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-tert-octyl-N-(((S)-3-(3-fluoro-4-morpholinophenyl)-2-oxazolidin-5-yl)methyl)acetamide(1215006-12-4)
• EPA Substance Registry System: N-tert-octyl-N-(((S)-3-(3-fluoro-4-morpholinophenyl)-2-oxazolidin-5-yl)methyl)acetamide(1215006-12-4)

Safety Data

• Hazardous Substances Data: 1215006-12-4(Hazardous Substances Data)

Upstream product

• 1215006-09-9 (S)-5-((tert-octylamino)methyl)-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one 
• 75-36-5 acetyl chloride 

Downstream Products

• 165800-03-3 linezolid 

Relevant articles and documents

Process for the preparation of an oxazolidinone antibacterial agent and intermediates thereof

Comprising a preparation process of linezolid from a compound of formula (IV) where R1 is selected from a (C4-C10)-alkyl radical which is attached to the N atom by a tertiary C atom, and a straight or branched (C3-C10)-alkenyl radical attached to the N atom such that the C=C double bond is separated from the N atom by a methylene group. Compound (IV) is submitted either first to an acetylation reaction and then to a dealkylation reaction or, alternatively, first to a dealkylation reaction and then to an acetylation reaction to yield linezolid. It also comprises new intermediate compounds useful in such a preparation process, which are obtained with high yields and high chemical and optical purity, and which are processed easily to linezolid.