121562-47-8

Basic information

• Product Name: 2H-Pyran-2-one,6-[(1E,3E,5E)-3,5-dimethyl- 6-phenyl-1,3,5-hexatrienyl]-4-methoxy-5- methyl-
• CAS NO: 121562-47-8
• Molecular Weight: 322.404
• Mol File: 121562-47-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2H-Pyran-2-one,6-[(1E,3E,5E)-3,5-dimethyl- 6-phenyl-1,3,5-hexatrienyl]-4-methoxy-5- methyl- (CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyran-2-one,6-[(1E,3E,5E)-3,5-dimethyl- 6-phenyl-1,3,5-hexatrienyl]-4-methoxy-5- methyl- (121562-47-8)
• EPA Substance Registry System: 2H-Pyran-2-one,6-[(1E,3E,5E)-3,5-dimethyl- 6-phenyl-1,3,5-hexatrienyl]-4-methoxy-5- methyl- (121562-47-8)

Safety Data

• Hazardous Substances Data: 121562-47-8(Hazardous Substances Data)

Upstream product

• 58550-29-1 2,4-dimethyl-5-phenyl-2,4-pentadienoic acid 
• 58550-30-4 ethyl (2E,4E)-2,4-dimethyl-5-phenylpenta-2,4-dienoate 
• 64361-40-6 4-methoxy-5.6-dimethyl-2H-pyran-2-one 
• 125454-78-6 (2E,4E)-2,4-dimethyl-5-phenylpenta-2,4-dienal 
• 50405-45-3 4-hydroxy-5,6-dimethyl-2H-pyran-2-one 
• 50496-43-0 ethyl 4-methyl-3,5-dioxohexanoate 

Downstream Products

• 65-85-0 benzoic acid 
• 121562-49-0 6-(3,5-Dimethyl-6-phenyl-hexyl)-4-methoxy-5-methyl-pyran-2-one 

Relevant articles and documents

Regioselective functionalization of pyrones: Facile synthesis of 6-styrylpyrones via KHMDS-mediated aldol condensation

Herein, we disclose our efforts directed toward the synthesis of the kavalactone-based natural product penstyrylpyrone and other related 4-OMe-2-pyrones possessing diverse substituents at the 3-, 5-, and 7-positions. Further, a facile approach to access 6-styrylpyrones via the KHMDS-mediated regioselective aldol condensation of 2-pyrones is described with moderate substrate scope and good to high yields (58–80%). The utility of this methodology was exemplified by the stereoselective construction of desmethoxyyangonin, asnipyrone A, and asnipyrone B.