1215986-09-6

Basic information

• Product Name: 4-(pyrrolidin-1-yl)pyrimidin-2-amine
• Synonyms: 4-(pyrrolidin-1-yl)pyrimidin-2-amine
• CAS NO: 1215986-09-6
• Molecular Formula: C₈H₁₂N₄
• Molecular Weight: 164.20768
• Mol File: 1215986-09-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 384.6±34.0 °C(Predicted)
• Appearance: /
• Density: 1.237±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 7.62±0.10(Predicted)
• CAS DataBase Reference: 4-(pyrrolidin-1-yl)pyrimidin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(pyrrolidin-1-yl)pyrimidin-2-amine(1215986-09-6)
• EPA Substance Registry System: 4-(pyrrolidin-1-yl)pyrimidin-2-amine(1215986-09-6)

Safety Data

• Hazardous Substances Data: 1215986-09-6(Hazardous Substances Data)

Usage

General Description

4-(pyrrolidin-1-yl)pyrimidin-2-amine is a chemical compound with the molecular formula C9H14N4. It is a pyrimidine derivative with a pyrrolidinyl group attached to the 4-position of the pyrimidine ring. 4-(pyrrolidin-1-yl)pyrimidin-2-amine has potential applications in medicinal chemistry as it may exhibit biological activity due to its structural features.

Upstream product

• 123-75-1 pyrrolidine 
• 3993-78-0 2-amino-4-chloropyrimidine 

Relevant articles and documents

SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS

Provided herein are novel substituted bicyclic aza-heterocycle sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.

SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS

Provided herein are novel substituted bicyclic aza-heterocycle sirtuin- modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin- modulating compound in combination with another therapeutic agent.