121613-69-2

Basic information

• Product Name: 1,2-O-isopropylidene-6-O-p-toluenesulfonyl-α-D-allofuranose
• CAS NO: 121613-69-2
• Molecular Weight: 374.412
• Mol File: 121613-69-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,2-O-isopropylidene-6-O-p-toluenesulfonyl-α-D-allofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-O-isopropylidene-6-O-p-toluenesulfonyl-α-D-allofuranose(121613-69-2)
• EPA Substance Registry System: 1,2-O-isopropylidene-6-O-p-toluenesulfonyl-α-D-allofuranose(121613-69-2)

Safety Data

• Hazardous Substances Data: 121613-69-2(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 121701-18-6 1,2-O-isopropylidene-α-L-glucofuranose 
• 582-52-5 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 2595-05-3 Diacetone D-glucose 
• 2280-44-6 D-Glucose 
• 582-52-5 1,2:5,6-di-O-isopropylidene-α-L-glucofuranose 

Downstream Products

• 4118-60-9 O¹,O²-isopropyliden-5,6-anhydro-α-L-glucofuranose 
• 1379771-63-7 1,2-O-isopropylidene-3,5-di-O-benzyl-6-azido-α-D-allofuranose 
• 1379771-66-0 tert-butyl 1-(2-(benzyloxy)-2-((3aR,5R,6aR)-6-(benzyloxy)-2,2-dimethyltetrahydro-furo[2,3-d][1,3]dioxol-5-yl)ethylamino)-3-methyl-1-oxobutan-2-ylcarbamate 

Relevant articles and documents

Sugar-amino acid cyclic conjugates as novel conformationally constrained hydroxyethylamine transition-state isosteres

Hydroxyethylamine (HEA) isosteres have previously been shown to display a multitude of biomedical applications. In fact, the first protease inhibitor, saquinavir is an HEA based peptidomimetic. Herein we describe an easy-to-operate synthetic route to a series of carbohydrate-based conformationally constrained hydroxyethylamine (HEA) isosteres featuring amino acid side chains, starting from d-glucose. This class of novel sugar-amino acid-tethered conformationally restricted HEA systems may have bearing in practical application, particularly in the development of conformationally restricted protease inhibitors.