121637-68-1

Basic information

• Product Name: 1-(3,4,5-trimethoxyphenyl)-2-bromopropane
• Synonyms: 1-(3,4,5-trimethoxyphenyl)-2-bromopropane
• CAS NO: 121637-68-1
• Molecular Weight: 289.169
• Mol File: 121637-68-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(3,4,5-trimethoxyphenyl)-2-bromopropane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,4,5-trimethoxyphenyl)-2-bromopropane(121637-68-1)
• EPA Substance Registry System: 1-(3,4,5-trimethoxyphenyl)-2-bromopropane(121637-68-1)

Safety Data

• Hazardous Substances Data: 121637-68-1(Hazardous Substances Data)

Upstream product

• 487-11-6 elemicin 

Downstream Products

• 61281-38-7 (+/-)-deoxyschizandrin 
• 50544-08-6 5,5'-(2,3-dimethylbutane-1,4-diyl)bis(1,2,3-trimethoxybenzene) 

Relevant articles and documents

Syntheses of (+/-)-Deoxyschizandrin and the Lignan, 1,4-Bis(3,4-dimethoxyphenyl)-2,3-dimethylbutane

(+/-)-Deoxyschizandrin (1) has been synthesised through a dimerisation reaction as a key step.The Grignard reagent from 1-(3,4,5-trimethoxyphenyl)-2-bromopropane (10) on reaction with 2-t-butyl-3-phenyloxaziridine gives 1,4-bis(3,4,5-trimethoxyphenyl)-2,3-dimethylbutane (11), which is cyclised using vanadium oxytrifluoride to get deoxyschizandrin (1).Following the above methodology, 1,4-bis(3,4-dimethoxyphenyl)-2,3-dimethylbutane (2), a lignan has also been prepared.