121671-81-6Relevant articles and documents
20-HETE RECEPTOR (GPR75) ANTAGONISTS AND METHODS OF USE
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, (2017/09/27)
The present invention concerns compounds and their use to treat cardiovascular disease, renal disease, thrombic disease, stroke, metabolic syndrome, cell proliferation, and ischemic cardiovascular disorders. Compounds of the present invention display sign
Total synthesis of two γ-butyrolactone containing compounds (Z,11S)-3,4-trans-11-hydroxy-3-methyldodec-cis-6-en-4-olide and (Z)-3,4-trans-11-oxo-3-methyldodec-cis-6-en-4-olide
Nomula, Rajesh,Raju, Galla,Radha Krishna, Palakodety
, p. 5976 - 5978 (2014/12/12)
The first total synthesis of (Z,11S)-3,4-trans-11-hydroxy-3-methyldodec-cis-6-en-4-olide and (Z)-3,4-trans-11-oxo-3-methyldodec-cis-6-en-4-olide was accomplished using Jacobsen hydrolytic kinetic resolution, Ohira-Bestmann reaction, regioselective alkyne
First stereoselective total synthesis of naturally occurring (6 R)-6-(4-Oxopentyl)-5,6-dihydro-2 H -pyran-2-one and Its (6 S)-enantiomer
Shinde, Digambar Balaji,Kanth, Boddu Shashi,Srilatha, Malampati,Das, Biswanath
, p. 469 - 473 (2012/03/26)
(6R)-6-(4-Oxopentyl)-5,6-dihydro-2H-pyran-2-one, a naturally occurring ,-unsaturated -lactone, and its (6S)-enantiomer have been synthesized stereoselectively starting from pentane-1,5-diol. The synthesis involves Maruoka asymmetric allylation and ring-cl