1217-99-8

Basic information

• Product Name: 5-methyl-1-(4-nitrophenyl)-1H-1,2,3-triazole-4-carboxylic acid
• Synonyms: 5-methyl-1-(4-nitrophenyl)-1H-1,2,3-triazole-4-carboxylic acid
• CAS NO: 1217-99-8
• Molecular Weight: 248.198
• Mol File: 1217-99-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 5-methyl-1-(4-nitrophenyl)-1H-1,2,3-triazole-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-1-(4-nitrophenyl)-1H-1,2,3-triazole-4-carboxylic acid(1217-99-8)
• EPA Substance Registry System: 5-methyl-1-(4-nitrophenyl)-1H-1,2,3-triazole-4-carboxylic acid(1217-99-8)

Safety Data

• Hazardous Substances Data: 1217-99-8(Hazardous Substances Data)

Upstream product

• 1516-60-5 4-nitrophenyl azide 
• 141-97-9 ethyl acetoacetate 
• 100-01-6 4-nitro-aniline 
• 541-50-4 2-acetoacetic acid 
• 15922-67-5 methyl 5-methyl-1-(4-nitrophenyl)-1H-1,2,3-triazole-4-carboxylate 

Downstream Products

• 1194641-17-2 1-[3-(4-bromophenyl)-2,1-benzisoxazol-5-yl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid 
• 1194641-14-9 1-[3-(4-fluorophenyl)-2,1-benzisoxazol-5-yl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid 
• 1017473-02-7 5-methyl-1-(3-phenyl-2,1-benzisoxazol-5-yl)-1H-1,2,3-triazole-4-carboxylic acid 
• 1017426-71-9 1-[3-(4-chlorophenyl)-2,1-benzisoxazol-5-yl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid 
• 88958-24-1 C₁₀H₇ClN₄O₃ 
• 1422423-73-1 4-(decyloxy)phenyl 5-methyl-1-(4-nitrophenyl)-1H-1,2,3-triazole-4-carboxylate 
• 950357-49-0 1-[3-(4-chlorophenyl)-2,1-benzoxazol-5-yl]-N-(furan-2-ylmethyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide 
• 951899-57-3 1-(3-(4-chlorophenyl)benzo[c]isoxazol-5-yl)-N-(3-methoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide 
• 924824-13-5 5-methyl-1-(3-phenyl-2,1-benzoxazol-5-yl)-N-[3-(trifluoromethyl)phenyl]-1H-1,2,3-triazole-4-carboxamide 
• 1207-25-6 5-methyl-1-(4-nitrophenyl)-1H-1,2,3-triazole 
• 84292-49-9 [4-(5-Methyl-[1,2,3]triazol-1-yl)-phenoxy]-acetic acid ethyl ester 
• 84292-48-8 1-(4-Hydroxyphenyl)-5-methyl-1,2,3-triazole 
• 84292-45-5 1-(4-Aminophenyl)-5-methyl-1,2,3-triazole 
• 84292-53-5 2-[4-(5-Methyl-4-phenyl-[1,2,3]triazol-1-yl)-phenoxy]-propionic acid 

Relevant articles and documents

The nitro aromatic compounds detection by triazole carboxylic acid and its complex with the fluorescent property

The 5-methyl-1-(4-nitrophenyl)-1H-1, 2, 3-triazole-4-carboxylic acid (1) was synthesized by an improved method. By using the compound 1 as ligand, a new complex [Cu(L)2][Cu(L)2(H2O)2] (2) was prepared firstly under hydrothermal condition. Both 1 and 2 were all used as exclusive fluorescence sensor for 2, 4, 6-trinitrophenol (TNP) for the first time. The fluorescence exploration demonstrated that they exhibit highly selective and sensitive (KSV?=?393685?M?1 and KSV?=?213269?M?1, respectively) sensing to TNP from other nitro aromatic compounds (NACs) with high quenching efficiency QP value of 96.76% and 93.37%, as well as low detection limit (0.68?μM and 0.37?μM, respectively). It means that complex 2 had higher selectivity due to the less interference by 4-NT and 2-NP compared with 1. Moreover, the fluorescence quenching phenomenon of sensor 1 with TNP was analyzed by density functional theory (DFT).

The synthesis of some new (S)-1-aryl-N-(1-hydroxy-3-phenylpropan-2-yl)-5- methyl-1H-1,2,3-triazole-4-carboxamide

Some new (S)-1-aryl-N-(1-hydroxy-3-phenylpropan-2-yl)-5-methyl-1 H-1,2,3-triazole-4-carboxamides 4a, 4b, 4c, 4d, 4e, 4f, 4g, 4h, 4i, 4j have been synthesized and established by 1H and 13C NMR, IR, MS spectra, CHN analyses, and x-ray

Synthesis of 2,1-benzisoxazoles by nucleophilic substitution of hydrogen in nitroarenes activated by the azole ring

Reaction of 1-nitro-4-(1,2,3-triazolyl/tetrazolyl)benzenes with arylacetonitriles in an alcoholic medium in the presence of excess alkali gives novel 2,1-benzisoxazoles. These findings indicate a high reactivity of nitroarenes activated by the azole ring due to their electron-deficient character. Moreover, it was found that annulation of the isoxazole ring occurred regioselectively in disubstituted nitroarenes. In the case of 1-(4-nitrophenyl)-1H-tetrazole, the tetrazole ring cleaved faster than the sH-adduct was formed. Georg Thieme Verlag Stuttgart.