121746-87-0

Basic information

• Product Name: 1,2-dimethoxy-3-(6-nitro-cyclohex-3-enyl)-benzene
• CAS NO: 121746-87-0
• Molecular Weight: 263.293
• Mol File: 121746-87-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2-dimethoxy-3-(6-nitro-cyclohex-3-enyl)-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-dimethoxy-3-(6-nitro-cyclohex-3-enyl)-benzene(121746-87-0)
• EPA Substance Registry System: 1,2-dimethoxy-3-(6-nitro-cyclohex-3-enyl)-benzene(121746-87-0)

Safety Data

• Hazardous Substances Data: 121746-87-0(Hazardous Substances Data)

Upstream product

• 106-99-0 buta-1,3-diene 
• 37630-20-9 1,2-Dimethoxy-3-((E)-2-nitro-vinyl)-benzene 

Downstream Products

• 854715-49-4 2-bromo-2-(2,3-dimethoxy-phenyl)-cyclohexanone 
• 408353-33-3 2-(2,3-dimethoxy-phenyl)-cyclohexylamine 
• 195001-56-0 2-(2,3-dimethoxyphenyl)cyclohex-2-en-1-one 
• 89756-87-6 2-(2,3-dimethoxyphenyl)-cyclohexanone 
• 859785-96-9 1,2-dimethoxy-3-(2-nitro-cyclohexyl)-benzene 
• 121746-90-5 6-(2,3-dimethoxy-phenyl)-cyclohex-3-enone 

Relevant articles and documents

Asymmetric Reductive Amination of Cycloalkanones, VII: Asymmetric Synthesis of cis-1R,2R- and cis-1S,2S,-2-Arylcyclohexanamines

The asymmetric synthesis of cis-2-arylcyclohexanamines 4 by a three-step procedure is reported: condensation of racemic 2-arylcyclohexanones 1 with the chiral auxiliary R-(+)- or S-(-)-1-phenylethylamine, respectively, leads to a mixture of the imin isomers 2.Upon hydrogenation with Raney-Nickel just one secondary amin of type 3 is obtained, which is hydrogenolyzed to the optically active primary cis-2-arylcyclohexanamines 4.The relative configuration as well as the conformation were derived from 1H-NMR data.The absolute configuration of the highly enantiomericallypure compounds 4 was determined by CD spectra.