1217738-82-3 Usage
General Description
Boc-6-chloro-D-tryptophan is a chemical compound characterized by the presence of both the Boc (tert-butoxycarbonyl) protecting group and the 6-chloro substitution on the D-tryptophan molecule. Boc-6-chloro-D-tryptophan is often used in organic synthesis and chemical research due to its potential for incorporation into various types of molecules and peptides. The Boc protecting group serves to block the reactive amine group on the tryptophan, allowing for selective chemical reactions to occur at other functional groups on the molecule. The 6-chloro substitution also imparts specific reactivity and characteristics to the compound, leading to its use in creating novel chemical structures and studying the biological activity of tryptophan-containing molecules. Overall, Boc-6-chloro-D-tryptophan is a versatile chemical with potential applications in the fields of pharmaceuticals, biochemistry, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 1217738-82-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,7,7,3 and 8 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1217738-82:
(9*1)+(8*2)+(7*1)+(6*7)+(5*7)+(4*3)+(3*8)+(2*8)+(1*2)=163
163 % 10 = 3
So 1217738-82-3 is a valid CAS Registry Number.
1217738-82-3Relevant articles and documents
Mild, Aqueous α-Arylation of Ketones: Towards New Diversification Tools for Halogenated Metabolites and Drug Molecules
Marelli, Enrico,Renault, Yohann,Sharma, Sunil V.,Nolan, Steven P.,Goss, Rebecca J. M.
, p. 3832 - 3836 (2017)
The palladium-catalysed aqueous α-arylation of ketones was developed and tested for a large variety of reaction partners. These mild conditions enabled the coupling of aryl/alkyl-ketones with N-protected halotryptophans, heterocyclic haloarenes, and challenging base-sensitive compounds. The synthetic potential of this new methodology for the diversification of complex bioactive molecules was exemplified by derivatising prochlorperazine. The methodology is mild, aqueous and flexible, representing a means of functionalizing a wide range of halo-aromatics and therefore has the potential to be extended to complex molecule diversification.
