1217809-88-5 Usage
General Description
(S)-Cinacalcet hydrochloride, commonly known as Cinacalcet, is a synthetic, hydrochloride salt form of cinacalcet with calcimimetic activity. It works by imitating the action of calcium on tissues in the body, primarily by increasing the sensitivity of the calcium-sensing receptor (CaSR) to activation by extracellular calcium. The overall effect is to regulate the body's production of parathyroid hormone, which can help control calcium levels in the blood and bones. This can benefit people with chronic kidney disease and hyperparathyroidism. The compound is generally administered orally and has a bitter taste.
Check Digit Verification of cas no
The CAS Registry Mumber 1217809-88-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,7,8,0 and 9 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1217809-88:
(9*1)+(8*2)+(7*1)+(6*7)+(5*8)+(4*0)+(3*9)+(2*8)+(1*8)=165
165 % 10 = 5
So 1217809-88-5 is a valid CAS Registry Number.
1217809-88-5Relevant articles and documents
Hydroxoiridium-Catalyzed Hydroalkylation of Terminal Alkenes with Ureas by C(sp3)?H Bond Activation
Yamauchi, Daisuke,Nishimura, Takahiro,Yorimitsu, Hideki
, p. 7200 - 7204 (2017)
Direct alkylation of a methyl group, on di- and trisubstituted ureas, with terminal alkenes by C(sp3)?H bond activation proceeded in the presence of a hydroxoiridium/bisphosphine catalyst to give high yields of the corresponding addition products. The hydroxoiridium/bisphosphine complex generates an amidoiridium intermediate by reaction with ureas having an N?H bond.
