121786-39-8Relevant articles and documents
METHOD OF PRODUCING OPTICALLY ACTIVE AMINO ACID DERIVATIVE
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Page/Page column 13-14, (2011/04/18)
The present application relates to a method for producing an optically active α-amino acid derivative, comprising steps of reacting an α-haloester derivative represented by the general formula (1): of which alcohol part of the ester group is an optically active alcohol derivative, with an amine compound; then deprotecting the obtained compound; further carrying out an ester exchange reaction. According to the present invention method, it is possible to easily produce an optically active α-amino acid ester derivative which is useful as an intermediate for drugs with high selectivity.
A practical method for the synthesis of D- or L-α-amino acids by the alkylation of (+)- or (-)-pseudoephedrine glycinamide
Myers, Andrew G.,Gleason, James L.,Yoon, Taeyoung
, p. 8488 - 8489 (2007/10/02)
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