121817-16-1

Basic information

• Product Name: 2-acetyl-3,5-dimethoxyphenyl-3,4,5-trimethoxyphenyl ester
• Synonyms: 2-acetyl-3,5-dimethoxyphenyl-3,4,5-trimethoxyphenyl ester
• CAS NO: 121817-16-1
• Molecular Weight: 390.39
• Mol File: 121817-16-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-acetyl-3,5-dimethoxyphenyl-3,4,5-trimethoxyphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-acetyl-3,5-dimethoxyphenyl-3,4,5-trimethoxyphenyl ester(121817-16-1)
• EPA Substance Registry System: 2-acetyl-3,5-dimethoxyphenyl-3,4,5-trimethoxyphenyl ester(121817-16-1)

Safety Data

• Hazardous Substances Data: 121817-16-1(Hazardous Substances Data)

Usage

Chemical structure

Phenyl ester formed from 2-acetyl-3,5-dimethoxyphenol and 3,4,5-trimethoxyphenol

Source

Found in certain plants such as Acorus calamus

Pharmacological properties

Studied for potential insecticidal properties and potential treatment of neurological disorders

Investigated for

potential role in cancer treatment and as a chemical precursor for the synthesis of other organic compounds

Controversial use

Due to potential toxicity and safety concerns

Upstream product

• 90-24-4 2-hydroxy-4,6-dimethoxyacetophenone 
• 4521-61-3 3,4,5-Trimethoxybenzoyl chloride 
• 480-66-0 2,4,6-trihydroxyacetophenone 

Downstream Products

• 84212-57-7 1-(4,6-dimethoxy-2-hydroxyphenyl)-3-(3,4,5-trimethoxyphenyl)propan-1,3-dione 
• 53350-26-8 5,7-Dimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-chromen-4-one 
• 520-31-0 tricetin 

Relevant articles and documents

Preparation method and application of tricetin

The invention belongs to the field of medicine synthesis, and in particular relates to a preparation method and application of tricetin. The method comprises the following steps: performing hydroxy protection to form a compound 3 by using 2,4,6-trihydroxyacetophenone as a starting material, performing an acylation reaction on the compound 3 and 3,4,5-trimethoxybenzoyl chloride to form a compound 4, performing Baker-Venkataranan rearrangement on the compound 4 to form a compound 5, performing cyclization on the compound 5 under catalysis of H2SO4/HOAc to form a compound 6, and finally performing pyridine hydrochloride deprotection on the compound 6 to form the tricetin, wherein in the step of synthesizing the compound 5, when NaOH is selected as a base and pyridine is selected as a solvent,the yield is greatly improved, and the reaction is relatively stable. According to the method provided by the invention, pharmacological activity experiments show that the compound synthesized by themethod has anti-nerve damage activity, so that the compound has better application prospects in treating nerve damage-related diseases.

Constituents of the Root Bark of Murraya paniculata Collected in Indonesia

A mixture of fatty acid esters (Va) of murrangatin was obtained from the root bark of Murraya paniculata (Rutaceae) collected in Indonesia together with eleven known constituents of chemotaxonomical significance, and their structures were characterized on